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Photonuclear production and radiochemical separation of medically relevant radionuclides: 67Cu

  • Ramiz A. AlievEmail author
  • Sergey S. Belyshev
  • Alexander A. Kuznetsov
  • Leonid Z. Dzhilavyan
  • Vadim V. Khankin
  • Gleb Yu. Aleshin
  • Andrey G. Kazakov
  • Anna B. Priselkova
  • Stepan N. Kalmykov
  • Boris S. Ishkhanov
Article

Abstract

Production of medical radionuclide 67Cu by the irradiation of Zn of natural isotopic composition by bremsstrahlung photons of maximum energy of 55 MeV was studied. Production yields of 67Cu and other activation products were determined. The yield of 67Cu is (2.34 ± 0.07) × 105 Bq/(μA h g/cm2) at EOB. The experimental data were compared with the results of other experiments and theoretical calculations based on the statistical model in the TALYS software and on the combined model of photonuclear reactions. Technique of chemical separation of 67Cu from irradiated zinc target based on extraction chromatography using CU Resin was applied. Radiochemical yield was > 95%, separation time was 1 h. The possibility of production of medical quantities was discussed.

Keywords

Copper-67 Radionuclide therapy Photonuclear reactions Extraction chromatography 

Notes

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Copyright information

© Akadémiai Kiadó, Budapest, Hungary 2019

Authors and Affiliations

  • Ramiz A. Aliev
    • 1
    • 2
    Email author
  • Sergey S. Belyshev
    • 3
  • Alexander A. Kuznetsov
    • 3
    • 5
  • Leonid Z. Dzhilavyan
    • 4
  • Vadim V. Khankin
    • 5
  • Gleb Yu. Aleshin
    • 2
  • Andrey G. Kazakov
    • 1
    • 2
  • Anna B. Priselkova
    • 5
  • Stepan N. Kalmykov
    • 1
    • 2
  • Boris S. Ishkhanov
    • 3
    • 5
  1. 1.National Research Center “Kurchatov Institute”MoscowRussia
  2. 2.Chemistry DepartmentLomonosov Moscow State UniversityMoscowRussia
  3. 3.Physics DepartmentLomonosov Moscow State UniversityMoscowRussia
  4. 4.Institute for Nuclear ResearchRussian Academy of SciencesMoscowRussia
  5. 5.Skobeltsyn Institute of Nuclear PhysicsLomonosov Moscow State UniversityMoscowRussia

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