Journal of Radioanalytical and Nuclear Chemistry

, Volume 318, Issue 2, pp 1001–1008 | Cite as

Assessment of 14C-sulfadiazine on Danio rerio (zebrafish)

  • Aline Trentini Da Silveira
  • Lucineide Aparecida Maranho
  • Nádia Hortense Torres
  • Luiz Fernando Romanholo Ferreira
  • Marilia Moura de Salles Pupo
  • Ram Naresh Bharagava
  • Bruno Santos Souza
  • Mônica Jones Costa
  • Valdemar Luiz Tornisielo


Antimicrobials, besides application in pharmaceuticals, are used as growth promoters in agriculture, especially for cattle, pigs, and poultry production, as well as, complement for fish in aquaculture. In addition to uses mentioned above, the improper disposal of these substances may cause problems in the aquatic environments such as bioaccumulation, bioconcentration and biomagnification. Thus, the aim of this study was to evaluate the bioconcentration and depuration of sulfadiazine using the teleost fish Danio rerio as test organism. During 20 days of exposal to 14C-sulfadiazine, a small amount of the antimicrobial concentration was observed on fish. Further, no depuration was noted during this period.


Sulfadiazine Bioconcentration Depuration Danio rerio 


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Copyright information

© Akadémiai Kiadó, Budapest, Hungary 2018

Authors and Affiliations

  • Aline Trentini Da Silveira
    • 1
    • 2
  • Lucineide Aparecida Maranho
    • 1
  • Nádia Hortense Torres
    • 1
    • 3
    • 4
  • Luiz Fernando Romanholo Ferreira
    • 3
    • 4
  • Marilia Moura de Salles Pupo
    • 3
    • 4
  • Ram Naresh Bharagava
    • 5
  • Bruno Santos Souza
    • 6
  • Mônica Jones Costa
    • 2
  • Valdemar Luiz Tornisielo
    • 1
  1. 1.Ecotoxicology Laboratory, Center for Nuclear Energy in AgricultureUniversity of Sao PauloPiracicabaBrazil
  2. 2.Federal University of São Carlos (UFSCar)SorocabaBrazil
  3. 3.Post-Graduated Program on Process EngineeringTiradentes UniversityAracajuBrazil
  4. 4.Institute of Technology and ResearchAracajuBrazil
  5. 5.Laboratory for Bioremediation and Metagenomics Research (LBMR), Department of Microbiology (DM)Babasaheb Bhimrao Ambedkar University (A Central University)LucknowIndia
  6. 6.Department of Environmental EngineeringFederal University of SergipeSão CristóvãoBrazil

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