Preparation of mechanically strong poly (ether block amide)/Mercaptoethanol breathable membranes for biomedical applications
- 47 Downloads
Poly (ether block amide) (PEBA) was modified with Mercaptoethanol (ME) to introduce crosslinks in its polymeric structure and emphasis was laid on obtaining non-porous breathable membranes with improved mechanical properties which can be used for various biomedical applications. Pebax MH 1657 (mentioned as PEBA throughout the text) was cast polymerized with ME and the effect of ME on the properties of the membranes (such as water absorption, permeability, tensile strength, elongation & tear strength) was studied. Fourier Transform Infrared Spectroscopy- Attenuated Total Reflectance (FTIR-ATR), Scanning Electron Microscopy (SEM), Atomic Force Microscopy (AFM), Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA) and Differential Thermogravimetry (DTG) techniques were used to characterize the membranes. Different amount of ME (10 to 40% w/w) was added to PEBA and 30% of ME was found to be most effective in increasing the mechanical properties of the membrane. Sulfhydryl group played an important role in enhancing mechanical strength of the membranes. PEBA/ME based non porous breathable membrane with excellent mechanical strength is a novel material that can be used for various biomedical applications.
KeywordsPoly (ether block amide) Mercaptoethanol Mechanical properties Breathable membrane Sulfhydryls Biomedical applications
The authors greatly acknowledge Shriram Institute for Industrial Research, New Delhi, India for providing chemicals and instrumentation to carry out this research. Thanks to Material Research Centre, Malaviya National Institute of Technology (MNIT) Jaipur (Rajasthan), India for AFM Analysis. A special thanks to Amity University Noida (UP), India for SEM analysis.
- 1.Larry J, Dirk S (2000) Breathable TPE membranes for medical applications. Medical Device & Diagnostic Industry MagazineGoogle Scholar
- 2.Wu PC, Jones G, Shelley C, Woelfli B (2007) Novel microporous films and their composites. J Eng Fibres Fabr 2:49–58Google Scholar
- 12.Rebecca B, Kevin M, Matthew HWT (2012) Cross-linking of Thiolated chitosan films: effects on the cell adhesion, degradation and cyclic mechanical properties. AIChE Annual Meeting, Materials Engineering and Sciences Division, Biomaterials IIGoogle Scholar
- 15.Hirschl C, Rydlo MB, DeBiasio M, Mühleisen W, Neumaier L, Scherf W, Oreski G, Eder G, Chernev B, Schwab W, Kraft M (2013) Determining the degree of crosslinking of ethylene vinyl acetate photovoltaic module encapsulants- a comparative study. Sol Energy Mater Sol Cells 116:203–218CrossRefGoogle Scholar
- 22.Maitra J, Shukla VK (2014) Cross-linking in Hydrogels - A Review. Am J Poly Sci 4:25–31Google Scholar
- 23.Nielsen LE (1969) Cross-linking–effect on physical properties of polymers, journal of macromolecular science. Part C: Polymer Reviews 3(1):69–103Google Scholar