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Journal of Polymers and the Environment

, Volume 27, Issue 12, pp 2933–2942 | Cite as

Polyvinyl Alcohol (PVA)–Azadirachta indica (Neem) Nanofibrous Mat for Biomedical Application: Formation and Characterization

  • Ayub AliEmail author
  • Md. Abdus Shahid
Original paper
  • 107 Downloads

Abstract

The present study provides credence to the formation of polyvinyl alcohol (PVA)–Azadirachta indica (neem) nanofibrous mat (PNNM) under optimum processing conditions of electrospinning technique from a mixer of PVA and neem extract to utilize the inherent medicinal properties of this herb for biomedical application. The bonding behavior, orientation of fibers, thermal behavior, and moisture management properties were evaluated by Fourier transforms infrared spectroscopy (FTIR), scanning electron microscopy (SEM), thermo gravimetric analysis (TGA) and moisture management tester (MMT) reports respectively. The antibacterial activity of the developed sample at the maximum mixing ratio of neem extract (80%) was tested against Gram-positive (S. aureus) bacteria using agar disc diffusion method. The results reveal that the prepared nanofibrous mat exhibited better thermal and moisture management properties in comparison with PVA nanofiber alone. The formation of smooth fibers was confirmed by SEM images having average diameter of 185 nm under 5k, 10k and 15k magnifications. The characteristic peaks of PVA and neem constituents in FTIR spectra of the developed mat confirmed the presence of both components. Bacterial resistance was reached up to 20 mm due to the antibacterial constituents of neem extract. Thus the developed mat could be used as a biocompatible and bio based in biomedical applications.

Graphic Abstract

Keywords

Neem extract Nanofibrous mat Electrospininning Bacterial resistance 

Notes

Acknowledgements

Department of Textile Engineering and Institute of Energy Engineering (IEE), DUET, Gazipur, Bangladesh is thankfully acknowledged. Sincere gratitude due to Waffen Research Laboratory (WRL), Dhaka for their unfailing support during the study.

Funding

No financial support has been received.

Compliance with Ethical Standards

Conflict of interest

On behalf of all authors, the corresponding author declares that there is no conflict of interest.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Textile EngineeringDhaka University of Engineering & Technology (DUET)DhakaBangladesh

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