Journal of Genetic Counseling

, Volume 24, Issue 3, pp 421–427 | Cite as

Creation of a Network to Promote Universal Screening for Lynch Syndrome: The Lynch Syndrome Screening Network

  • Sarah MangeEmail author
  • Cecelia Bellcross
  • Deborah Cragun
  • Deb Duquette
  • Lisa Gorman
  • Heather Hampel
  • Kory Jasperson


The Evaluation of Genomic Applications in Practice and Prevention Working Group published an evidence-based recommendation stating that every newly diagnosed colorectal cancer (CRC) should undergo tumor screening for Lynch syndrome (LS). In 2011, leading cancer institutions and public health agencies created the Lynch Syndrome Screening Network (LSSN) in order to promote routine LS screening on all newly diagnosed CRCs and endometrial cancers (EC). The LSSN facilitates implementation of appropriate screening via shared resources, protocols and data through network collaboration. The LSSN website contains resources for institutions interested in initiating screening, including materials for program development, implementation and sustainability. The LSSN listserv gives providers access to experts in LS screening and implementation. The LSSN database will allow exploration of key gaps in implementation as a consortia-wide endeavor. To date, the LSSN’s membership includes 85 institutions involved in the care of CRC patients and nine official partners such as national and state public health entities and other non-profit institutions. Nearly 80 % of the LSSN’s members have already implemented routine or universal CRC and/or EC screening. LSSN serves to further the population health potential of universal LS screening through collaborative efforts and resources.


Lynch syndrome Universal screening Colon cancer Endometrial cancer Genetic testing Genetic counseling 



Support for logistical needs of the LSSN has been provided in part by the NCI’s Epidemiology and Genomics Research Program (EGRP) in the Division of Cancer Control and Population Sciences (DCCPS). Support for Deborah Cragun’s work was provided by an NCI training grant to Moffitt Cancer Center (R25T 5R25CA147832-04).

Conflict of Interest

Sarah Mange, Cecelia Bellcross, Deborah Cragun, Deb Duquette, Lisa Gorman, Heather Hampel, Kory Jasperson declare that they have no conflict of interest.


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Copyright information

© National Society of Genetic Counselors, Inc. 2014

Authors and Affiliations

  • Sarah Mange
    • 1
    Email author
  • Cecelia Bellcross
    • 2
  • Deborah Cragun
    • 3
  • Deb Duquette
    • 1
  • Lisa Gorman
    • 4
  • Heather Hampel
    • 5
  • Kory Jasperson
    • 6
  1. 1.Lifecourse Epidemiology and Genomics DivisionMichigan Dept. of Community HealthLansingUSA
  2. 2.Human GeneticsEmory University School of MedicineAtlantaUSA
  3. 3.Department of Cancer Epidemiology, H. Lee Moffitt Cancer CenterTampaUSA
  4. 4.Michigan Public Health InstituteOkemosUSA
  5. 5.Division of Human Genetics, Department of Internal MedicineOhio State University Comprehensive Cancer CenterColumbusUSA
  6. 6.Huntsman Cancer InstituteUniversity of UtahSalt Lake CityUSA

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