Advertisement

The Impact of Deep Brain Stimulation for Parkinson’s Disease on Couple Satisfaction: An 18-Month Longitudinal Study

  • Marc BaertschiEmail author
  • Nicolas Favez
  • João Flores Alves Dos Santos
  • Michalina Radomska
  • François Herrmann
  • Pierre Burkhard
  • Alessandra Canuto
  • Kerstin Weber
Article
  • 26 Downloads

Abstract

Patients with Parkinson’s disease (PD) may benefit from deep brain stimulation (DBS) to improve motor and medication-induced symptoms. Yet mixed evidence regarding the outcome of successful DBS on couple satisfaction has been highlighted in the literature. Thirty patients diagnosed with PD were included in a study investigating couple satisfaction (MSS-14), depression (HAD-D) and anxiety (HAD-A) at four measurement times: before DBS and 6, 12, and 18 months post-surgically. Sixteen spouses/partners were included as well. Couple satisfaction from the patient perspective was never associated with depression or anxiety. However, poor marital adjustment (i.e., difference and absolute difference between patients and spouses/partners MSS-14 scores) predicted patients’ pre-operative depressive mood. Longitudinal analyses showed that couple satisfaction (n = 9) worsened at 12 months and 18 months compared to pre-DBS scores, F(2.047, 16.378) = 8.723, p = .003, and despite concomitant motor improvement. Growth curve analyses showed that couple satisfaction worsening occurred between 6 and 12 months post-operatively (b = 2.938, p < .001). Thus, couple satisfaction did not increase along with motor improvement and deteriorated after the adjustment period following DBS.

Keywords

Couple satisfaction Parkinson’s disease Deep brain stimulation Longitudinal 

Notes

Acknowledgements

This work was supported by the Swiss National Science Foundation (Grant No.: CR31I3_149578/1).

Compliance with Ethical Standards

Conflict of interest

The authors Marc Baertschi, Nicolas Favez, João Flores Alves Dos Santos, Michalina Radomska, François Herrmann, Pierre Burkhard, Alessandra Canuto, and Kerstin Weber declare that they have no conflict of interest.

Human and Animal Rights

All procedures were in accordance with the ethical standards of the institutional research committees and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

References

  1. Agid, Y., Schüpbach, M., Gargiulo, M., Mallet, L., Houeto, J. L., Behar, C., … Welter, M. L. (2006). Neurosurgery in Parkinson’s disease: The doctor is happy, the patient less so? Journal of Neural Transmission.  https://doi.org/10.1007/978-3-211-45295-0_61.Google Scholar
  2. Baertschi, M., Flores Alves Dos Santos, J., Tissot, H., Canuto, A., Favez, N., & Weber, K. (2017). Validation française d’une version brève de l’Échelle de satisfaction maritale. Revue Europeenne de Psychologie Appliquee, 67(4), 207–212.  https://doi.org/10.1016/j.erap.2017.05.002.CrossRefGoogle Scholar
  3. Bell, E., Maxwell, B., McAndrews, M. P., Sadikot, A. F., & Racine, E. (2011). A review of social and relational aspects of deep brain stimulation in Parkinson’s disease informed by healthcare provider experiences. Parkinson’s Disease, 2011, 871874.  https://doi.org/10.4061/2011/871874.Google Scholar
  4. Bidwell, J. T., Lyons, K. S., Mudd, J. O., Gelow, J. M., Chien, C. V., Hiatt, S. O., … Lee, C. S. (2017). Quality of life, depression, and anxiety in ventricular assist device therapy: Longitudinal outcomes for patients and family caregivers. Journal of Cardiovascular Nursing, 32(5), 455–463.  https://doi.org/10.1097/JCN.0000000000000378.CrossRefGoogle Scholar
  5. Bidwell, J. T., Lyons, K. S., Mudd, J. O., Grady, K. L., Gelow, J. M., Hiatt, S. O., … Lee, C. S. (2018). Patient and caregiver determinants of patient quality of life and caregiver strain in left ventricular assist device therapy. Journal of the American Heart Association, 7(6), 1–10.  https://doi.org/10.1161/JAHA.117.008080.CrossRefGoogle Scholar
  6. Bladin, P. F. (1992). Psychosocial difficulties and outcome after temporal lobectomy. Epilepsia, 33(5), 898–907.  https://doi.org/10.1111/j.1528-1157.1992.tb02198.x.CrossRefGoogle Scholar
  7. Boel, J. A., Odekerken, V. J. J., Schmand, B. A., Geurtsen, G. J., Cath, D. C., Figee, M., … de Bie, R. M. A. (2016). Cognitive and psychiatric outcome 3 years after globus pallidus pars interna or subthalamic nucleus deep brain stimulation for Parkinson’s disease. Parkinsonism and Related Disorders, 33, 90–95.  https://doi.org/10.1016/j.parkreldis.2016.09.018.CrossRefGoogle Scholar
  8. Edwards, N. E., & Ruettiger, K. M. (2002). The influence of caregiver burden on patients’ management of Parkinson’ s disease. Implications for Rehabilitation Nursing, 27(5), 182–187.CrossRefGoogle Scholar
  9. Flores Alves Dos Santos, J., Tezenas du Montcel, S., Gargiulo, M., Behar, C., Montel, S., Hergueta, T., … Welter, M.-L. (2017). Tackling psychosocial maladjustment in Parkinson’s disease patients following subthalamic deep-brain stimulation: A randomised clinical trial. PLoS ONE, 12(4), e0174512.  https://doi.org/10.1371/journal.pone.0174512.CrossRefGoogle Scholar
  10. Gilbert, F. (2012). The burden of normality: From “chronically ill” to “symptom free”. New ethical challenges for deep brain stimulation postoperative treatment. Journal of Medical Ethics, 38(7), 408–412.  https://doi.org/10.1136/medethics-2011-100044.CrossRefGoogle Scholar
  11. Haahr, A., Kirkevold, M., Hall, E. O. C., & Østergaard, K. (2010). From miracle to reconciliation: A hermeneutic phenomenological study exploring the experience of living with Parkinson’s disease following deep brain stimulation. International Journal of Nursing Studies, 47(10), 1228–1236.  https://doi.org/10.1016/j.ijnurstu.2010.03.006.CrossRefGoogle Scholar
  12. Haahr, A., Kirkevold, M., Hall, E. O. C., & Østergaard, K. (2013). “Being in it together”: Living with a partner receiving deep brain stimulation for advanced Parkinson’s disease—A hermeneutic phenomenological study. Journal of Advanced Nursing, 69(2), 338–347.  https://doi.org/10.1111/j.1365-2648.2012.06012.x.CrossRefGoogle Scholar
  13. Hely, M. A., Morris, J. G. L., Reid, W. G. J., & Trafficante, R. (2005). Sydney multicenter study of Parkinson’s disease: Non-L-dopa-responsive problems dominate at 15 years. Movement Disorders, 20(2), 190–199.  https://doi.org/10.1002/mds.20324.CrossRefGoogle Scholar
  14. Houeto, J.-L., Mallet, L., Mesnage, V., Tezenas du Montcel, S., Béhar, C., Gargiulo, M., … Agid, Y. (2006). Subthalamic stimulation in Parkinson disease: Behavior and social adaptation. Archives of Neurology, 63(8), 1090–1095.  https://doi.org/10.1001/archneur.63.8.1090.CrossRefGoogle Scholar
  15. Houeto, J.-L., Mesnage, V., Mallet, L., Pillon, B., Gargiulo, M., du Moncel, S. T., … Agid, Y. (2002). Behavioural disorders, Parkinson’s disease and subthalamic stimulation. Journal of Neurology, Neurosurgery, and Psychiatry, 72(6), 701–707. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/12023409.
  16. Jankovic, J. (2008). Parkinson’s disease: Clinical features and diagnosis. Journal of Neurology, Neurosurgery, and Psychiatry, 79(4), 368–376.  https://doi.org/10.1136/jnnp.2007.131045.CrossRefGoogle Scholar
  17. Kim, H.-Y. (2013). Statistical notes for clinical researchers: Assessing normal distribution (2) using skewness and kurtosis. Restorative Dentistry & Endodontics, 38(1), 52–54.  https://doi.org/10.5395/rde.2013.38.1.52.CrossRefGoogle Scholar
  18. Lyons, K. S., & Lee, C. S. (2018). The theory of dyadic illness management. Journal of Family Nursing, 24(1), 8–28.  https://doi.org/10.1177/1074840717745669.CrossRefGoogle Scholar
  19. Lyons, K. S., Stewart, B. J., Archbold, P. G., Carter, J. H., & Perrin, N. A. (2004). Pessimism and optimism as early warning signs for compromised health for caregivers of patients with Parkinson’s disease. Nursing Research, 53(6), 354–362.  https://doi.org/10.1097/00006199-200411000-00002.CrossRefGoogle Scholar
  20. Miller, E., Berrios, G. E., & Politynska, B. E. (1996). Caring for someone with Parkinson’s disease: Factors that contribute to distress. International Journal of Geriatric Psychiatry, 11(3), 263–268.CrossRefGoogle Scholar
  21. Obeso, J. A., Olanow, C. W., & Nutt, J. G. (2000). Levodopa motor complications in Parkinson’s disease. Trends in Neurosciences, 23(00), S2–S7.  https://doi.org/10.1016/S1471-1931(00)00031-8.CrossRefGoogle Scholar
  22. Perozzo, P., Rizzone, M., Bergamasco, B., Castelli, L., Lanotte, M., Tavella, A., … Lopiano, L. (2001). Deep brain stimulation of subthalamic nucleus: Behavioural modifications and familiar relations. Neurological Sciences, 22(1), 81–82.  https://doi.org/10.1007/s100720170057.CrossRefGoogle Scholar
  23. Pollak, P. (2013). Deep brain stimulation for Parkinson’s disease—Patient selection. In Handbook of clinical neurology (vol. 116, 1st ed.). Edinburgh: Elsevier.  https://doi.org/10.1016/B978-0-444-53497-2.00009-7.Google Scholar
  24. Roach, A. J., Frazier, L. P., & Bowden, S. R. (1981). The Marital Satisfaction Scale: Development of a measure for intervention research. Journal of Marriage and the Family, 43(3), 537–546.  https://doi.org/10.2307/351755.CrossRefGoogle Scholar
  25. Schüpbach, W. M. M., Gargiulo, M., Welter, M. L., Mallet, L., Béhar, C., Houeto, J. L., … Agid, Y. (2006). Neurosurgery in Parkinson disease: A distressed mind in a repaired body? Neurology.  https://doi.org/10.1212/01.wnl.0000234880.51322.16.Google Scholar
  26. Schüpbach, W. M. M., Rau, J., Knudsen, K., Volkmann, J., Krack, P., Timmermann, L., … Deuschl, G. (2013). Neurostimulation for Parkinson’s disease with early motor complications. The New England Journal of Medicine, 368(7), 610–622.  https://doi.org/10.1056/NEJMoa1205158.CrossRefGoogle Scholar
  27. Spiegelhalter, A. R., Abrams, K. R., & Myles, J. P. (2004). Bayesian approaches to clinical trials and health-care evaluation. Chichester: Wiley.Google Scholar
  28. Tysnes, O. B., & Storstein, A. (2017). Epidemiology of Parkinson’s disease. Journal of Neural Transmission, 124(8), 901–905.  https://doi.org/10.1007/s00702-017-1686-y.CrossRefGoogle Scholar
  29. Untas, A., Aguirrezabal, M., Chauveau, P., Leguen, E., Combe, C., & Rascle, N. (2009). Anxiété et dépression en hémodialyse: Validation de l’Hospital Anxiety and Depression Scale (HADS). Nephrologie et Therapeutique, 5(3), 193–200.  https://doi.org/10.1016/j.nephro.2009.01.007.CrossRefGoogle Scholar
  30. Van der Bruggen, H., & Widdershoven, G. (2004). Being a Parkinson’s patient: Immobile and unpredictably whimsical. Literature and existential analysis. Medicine, Health Care and Philosophy, 7, 289–301.CrossRefGoogle Scholar
  31. Vingerhoets, F. J. G., Villemure, J.-G., Temperli, P., Pollo, C., Pralong, E., & Ghika, J. (2002). Subthalamic DBS replaces levodopa in Parkinson’s disease: Two-year follow-up. Neurology, 58(3), 396–401.CrossRefGoogle Scholar
  32. Voon, V., & Fox, S. H. (2007). Medication-related impulse control and repetitive behaviors in Parkinson disease. Archives of Neurology, 64(8), 1089–1096.  https://doi.org/10.1097/WCO.0b013e32826fbc8f.CrossRefGoogle Scholar
  33. Williams, A., Gill, S., Varma, T., Jenkinson, C., Quinn, N., Mitchell, R., … Wheatley, K. (2010). Deep brain stimulation plus best medical therapy versus best medical therapy alone for advanced Parkinson’s disease (PD SURG trial): A randomised, open-label trial. The Lancet Neurology, 9(6), 581–591.  https://doi.org/10.1016/S1474-4422(10)70093-4.CrossRefGoogle Scholar
  34. Wilson, S. J., Saling, M. M., Kincade, P., & Bladin, P. F. (1998). Patient expectations of temporal lobe surgery. Epilepsia, 39(2), 167–174.  https://doi.org/10.1111/j.1528-1157.1998.tb01354.x.CrossRefGoogle Scholar
  35. Zigmond, A. S., & Snaith, R. P. (1983). The hospital anxiety and depression scale. Acta Psychiatrica Scandinavica, 67(6), 361–370.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Faculty of PsychologyUniversity of GenevaGenevaSwitzerland
  2. 2.Service of General Psychiatry and PsychotherapyNant FoundationMontreuxSwitzerland
  3. 3.Service of Liaison Psychiatry and Crisis InterventionGeneva University HospitalsGenevaSwitzerland
  4. 4.Liaison Psychiatry and Emergency Psychiatric CenterNeuchatel Psychiatric CenterNeuchâtelSwitzerland
  5. 5.Division of GeriatricsGeneva University HospitalsThônexSwitzerland
  6. 6.Service of NeurologyGeneva University HospitalsGenevaSwitzerland
  7. 7.Executive and General Management ServiceHôpital de Nant, Nant FoundationCorsier-sur-VeveySwitzerland
  8. 8.Division of Institutional Measures, Medical DirectionGeneva University HospitalsChêne-BourgSwitzerland

Personalised recommendations