A Green Systematic Approach of Carbon/CuO Nano Composites Using Aristolochia bracteolate by Response Surface Methodology

  • Selvaraj Mohana RoopanEmail author
  • Harsh Sharma
  • Gaurav Kumar
  • Abhishek Mishra
  • Venu Agarwal
  • Harsshit Agrawaal
  • Ganesh Elango
  • Kasinathan Irukatla Damodharan
  • Kuppuswamy Elumalai
Original Paper


The objective of this work is eco-friendly synthesis of Carbon/Copper oxide nano composites (C/CuO nano composites) from the aqueous extract of Aristolochia bracteolata (ABLPAE) via response surface methodology (RSM). Here we optimized various parameters to find out the absorption maximum value using RSM technique. Then the synthesized C/CuO nano composites were processed using different analytical tools. The crystanality of C/CuO was investigated using XRD analysis which exhibited crystalline size of 43 ± 2 nm. Additionally, synthesized C/CuO nano composites were used to study larvicidal activity using MANOVA; LSD-DMRT test. We found that results showed LC50 value at 26.42 ppm and 86.13 ppm for LC90. Ovicidal activity by anti-feedant method resulted in a dose dependent manner with a high mortality rate at higher concentrations.


Aristolochia bracteolata C/CuO nano composites RSM technique Larvicidal Ovicidal activity 


Compliance with Ethical Standards

Conflict of interest

Authors stated that there is no conflict of interest regarding this publication in your reputed journal.

Supplementary material

10876_2019_1613_MOESM1_ESM.docx (2.2 mb)
Supplementary material 1 (DOCX 2235 kb)


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Selvaraj Mohana Roopan
    • 1
    Email author
  • Harsh Sharma
    • 1
  • Gaurav Kumar
    • 1
  • Abhishek Mishra
    • 1
  • Venu Agarwal
    • 1
  • Harsshit Agrawaal
    • 2
  • Ganesh Elango
    • 1
    • 3
  • Kasinathan Irukatla Damodharan
    • 4
  • Kuppuswamy Elumalai
    • 4
  1. 1.Chemistry of Heterocycles and Natural Product Research Laboratory, Department of Chemistry, School of Advanced SciencesVellore Institute of TechnologyVelloreIndia
  2. 2.Department of Chemistry and BiochemistryTexas Tech UniversityLubbockUSA
  3. 3.Department of BiotechnologyJaya College of Arts and ScienceThiruninravur, ChennaiIndia
  4. 4.Department of Advanced Zoology and BiotechnologyGovt. Arts College (Autonomous)Nandanam, ChennaiIndia

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