Translation of basic research in cognitive science to HIV-risk: a randomized controlled trial
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Many people enrolled in drug diversion programs are not receiving evidence-based prevention for HIV or hepatitis. This study translated basic research from cognitive science to increase screening for infection and condom use in this population. A parallel three-condition randomized trial was conducted in a drug diversion sample (N = 358), comparing a memory practice condition with two active control conditions. Outcomes were condom use frequency and testing for infection (hepatitis B/C, HIV). At 3-month follow-up, participants in the memory practice condition were at least twice as likely (OR = 2.10 or greater, p < .01) to self-report testing compared to those in the control conditions and also reported more frequent condom use compared to a health education condition [B = .37, t(1) = 2.02, p = .02]. Basic research on memory can be effectively translated to brief interventions on infection screening and risk prevention in existing drug diversion programs.
KeywordsCognitive science HIV/AIDS Hepatitis Screening Condom use
The authors thank AIDS.videos.org for their educational videos, Susan Ames, Jerry Grenard, and Peter Graf for advice about some of the procedures, and Amy Custer, Sulay Gomez, and Octavia Freeman for assistance with the manuscript, computer programming, and data collection.
Research reported in this publication was supported by grants from the National Institute on Drug Abuse awarded to Alan Stacy (R01DA033871) and from the National Institute of Alcohol Abuse and Alcoholism awarded to Mary Larimar partially supporting Yusuke Shono (T32AA007455). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Compliance with ethical standards
Conflict of interest
Alan W. Stacy, Liesl A. Nydegger and Yusuke Shono declare that they have no conflict of interest.
Human and animal rights and Informed consent
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study.
- Branson, B. M., Handsfield, H. H., Lampe, M. A., Janssen, R. S., Taylor, A. W., Lyss, & S. B. (2006). Revised recommendations for HIV testing of adults, adolescents, and pregnant women in health-care settings. In WR. Recommendations and reports: Morbidity and mortality weekly report. Recommendations and reports/centers for disease control, 55(RR-14) (pp. 1–17).Google Scholar
- Caligiore, D., Mustile, M., Spalletta, G., & Baldassarre, G. (2017). Action observation and motor imagery for rehabilitation in Parkinson’s disease: A systematic review and an integrative hypothesis. Neuroscience and Biobehavioral Reviews, 72, 210–222. https://doi.org/10.1016/j.neubiorev.2016.11.005 CrossRefGoogle Scholar
- Calsyn, D. A., Hatch-Maillette, M., Tross, S., Doyle, S. R., Crits-Christoph, P., Song, Y. S., et al. (2009). Motivational and skills training HIV/sexually transmitted infection sexual risk reduction groups for men. Journal of Substance Abuse Treatment, 37, 138–150. https://doi.org/10.1016/j.jsat.2008.11.008 CrossRefGoogle Scholar
- Centers for Disease Control and Prevention. (2018). HIV in the United States: At a glance. Retrieved from https://www.cdc.gov/hiv/statistics/overview/ataglance.html. Accessed June 14, 2018.
- Donenberg, G. R., Emerson, E., Bryant, F. B., Wilson, H., & Weber-Shifrin, E. (2001). Understanding AIDS-risk behavior among adolescents in psychiatric care: Links to psychopathology and peer relationships. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 642–653.CrossRefGoogle Scholar
- Festinger, D. S., Dugosh, K. L., Metzger, D. S., & Marlowe, D. B. (2012). The prevalence of HIV risk behaviors among felony drug court participants. Drug Court Review, 8, 131–146.Google Scholar
- Fishbein, D. H., Ridenour, T. A., Stahl, M., & Sussman, S. (2016). The full translational spectrum of prevention science: Facilitating the transfer of knowledge to practices and policies that prevent behavioral health problems. Translational Behavioral Medicine, 6, 5–16. https://doi.org/10.1007/s13142-10.1177/1745691613498098 CrossRefGoogle Scholar
- Global Life Works. (2012). Collaborations. Retrieved from http://www.GlobalLifeworks.org/about/partners.cfm. Accessed August 1, 2012.
- Graham, J. W., Flay, B. R., Johnson, C. A., Hansen, W. B., Grossman, L., & Sobel, J. (1984). Reliability of self-report measures of drug use in prevention research: Evaluation of the project SMART questionnaire via the test-retest reliability matrix. Journal of Drug Education, 14, 175–193.CrossRefGoogle Scholar
- Hser, Y.-I., Teruya, C., Evans, E. A., Longshore, D., Grella, C., & Farabee, D. (2003). Treating drug-abusing offenders: Initial findings from a five-county study on the impact of California’s Proposition 36 on the treatment system and patient outcomes. Evaluation Review, 27, 479–505. https://doi.org/10.1177/0193841x03255774 CrossRefGoogle Scholar
- Longshore, D., Urada, D., Evans, E., Hser, Y., Prendergast, M., & Hawken, A. (2005). Evaluation of substance abuse and crime prevention act: 2004 report. Los Angeles, CA: Department of Alcohol and Drug Programs, California Health and Human Services Agency.Google Scholar
- Shoptaw, S., Montgomery, B., Williams, C. T., El-Bassel, N., Aramrattana, A., Metsch, L., et al. (2013). Not just the needle: The state of HIV prevention science among substance users and future directions. Journal of Acquired Immune Deficiency Syndromes (1999), 63, S174–S178. https://doi.org/10.1097/qai.0b013e3182987028 CrossRefGoogle Scholar
- Tross, S., Campbell, A. N., Cohen, L. R., Calsyn, D., Pavlicova, M., Miele, G. M., et al. (2008). Effectiveness of HIV/STD sexual risk reduction groups for women in substance abuse treatment programs: Results of NIDA clinical trials network trial. Journal of Acquired Immune Deficiency Syndromes (1999), 48, 581–589. https://doi.org/10.1097/QAI.0b013e31817efb6e CrossRefGoogle Scholar
- Workowski, K. A., Berman, S., & Centers for Disease Control and Prevention (CDC). (2010). Sexually transmitted diseases treatment guidelines, 2010. In MMWR. Recommendations and reports: Morbidity and mortality weekly report. Recommendations and Reports/Centers for Disease Control, 59(RR-12) (pp. 1–110).Google Scholar