Fabrication the hybrization of ZnO nanorods–Graphene nanoslices and their electrochemical properties to Levodopa in the presence of uric acid

  • Jianjiao ZhangEmail author
  • Qizhao Wang
  • Zhijie Sun
  • Bateer Buhe
  • Xinhao He


In this paper, graphene foam and ZnO nanorods were prepared by chemical vapor deposition (CVD) and hydrothermal processes, respectively. The hybrids of graphene nanoslices and ZnO nanorods were then fabricated by ultrasonic process. The as-prepared hybrids were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD) and Raman spectroscopy. The hybrids possess a slice-like structure with a smooth surface and rod structure, and the lengths of graphene nanoslices are about 3–4 µm. XRD results demonstrated the products are pure without impurities. Raman spectra showed that graphene has a few layers and defect free. The electrical performances of hybrids/ITO electrodes were investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The sensitivities of the electrode for LD detection are 0.19 and 0.20 µA µM−1 under the interruption of with UA and without UA. The results show that the electrode has good selectivity, reproducibility and stability which would be potential for use in future clinical research.



This work is supported by the Doctoral Scientific Research Fund of Heilongjiang Institute of Technology (2014BJ14) and the Student innovation and entrepreneurship training program of Heilongjiang Province (201611802114).


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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.College of Materials and Chemical EngineeringHeilongjiang Institute of TechnologyHarbinPeople’s Republic of China
  2. 2.Center for Biomedical Materials and EngineeringHarbin Engineering UniversityHarbinPeople’s Republic of China
  3. 3.School of Materials Science and EngineeringHarbin Institute of TechnologyHarbinPeople’s Republic of China

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