Ultra-long ZnO/carbon nanofiber as free-standing electrochemical sensor for dopamine in the presence of uric acid
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Dopamine (DA) and uric acid (UA) have similar peak potentials in vivo, and it is difficult to distinguish them by general electrode material. Here, we used a magnetron sputtering method to sputter the ZnO seed layer on carbon fiber and prepare ultra-long ZnO nanofibers/carbon fibers (ZnO NF/CF) electrode by in situ hydrothermal method. As a free-standing electrode, not only electrochemical detection of DA and UA but also a separation of oxidation potential peaks of DA and UA can be achieved. In addition, in the case of high concentration UA (0.1 mM), ZnO NF/CF shows high sensitivity and selectivity and shows a wide linear range for DA (4–20 µM). Meanwhile, we proposed the electrochemical mechanism and process of DA and UA on the surface of ZnO, which helps us to understand the simultaneous detection of DA and UA by such electrochemical electrodes.
This work was supported by the National Natural Science Foundation of China (Grant Nos. 91644103, 41603104, 61404075), the National Key Research and Development Program of China (2017YFC0212302), the Postdoctoral Foundation of Jiangsu Province (1601090B), the China Postdoctoral Science Foundation (2016M601694), and the Natural Science Foundation for Young Scientists of Jiangsu Province, China (BK20150895). Also including the Program for Changjiang Scholars and Innovative Research Team in University of Ministry of Education of China (PCSIRT) and the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD). At the same time, we also thank Professor Yanlin Zhang for his support and discussion.
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Conflict of interest
All the authors have declared that: (1) no support, financial or otherwise, has been received from any organization that may have an interest in the submitted work, and (2) there are no other relationships or activities that could appear to have influenced the submitted work.
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