Journal of Materials Science

, Volume 46, Issue 22, pp 7335–7343 | Cite as

Improving bioactivity and durability of yttria-stabilized zirconia

  • Miho NakamuraEmail author
  • Masahiro Inuzuka
  • Kazuaki Hashimoto
  • Akiko Nagai
  • Kimihiro Yamashita


Because of its excellent mechanical properties, yttria-stabilized zirconia is currently used as an orthopedic and dental material. In this study, we have improved the bioactivity of yttria-stabilized zirconia by a combination of electrical polarization and chemical treatment. The phase transformation from tetragonal to monoclinic ZrO2 after alkaline treatment was inhibited on positively charged yttria-stabilized zirconia surfaces compared with negatively charged and conventional surfaces. During polarization, some oxide ions move from the positively charged surface to the negatively charged surface, leading to an increase in oxygen vacancies on the positive surface and hence greater formation of Zr–OH when this surface was exposed to alkaline solution. This then reduced the water adsorption at this surface and consequently reduced the rate of cleavage of Zr–O–Zr bonds. The bioactivity was assessed by immersing the samples in simulated body fluid and evaluating the growth of apatite on the surfaces. The combination of polarization and alkaline treatment increased the bioactivity in vitro.


Simulated Body Fluid Alkaline Treatment Simulated Body Fluid Solution Tetragonal ZrO2 Thermally Stimulate Depolarization Current 


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Miho Nakamura
    • 1
    Email author
  • Masahiro Inuzuka
    • 1
    • 2
  • Kazuaki Hashimoto
    • 2
  • Akiko Nagai
    • 1
  • Kimihiro Yamashita
    • 1
  1. 1.Institute of Biomaterials and BioengineeringTokyo Medical and Dental UniversityChiyoda, TokyoJapan
  2. 2.Department of Life and Environmental ScienceChiba Institute of TechnologyChibaJapan

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