Journal of Materials Science

, Volume 41, Issue 15, pp 4974–4977 | Cite as

Self-assembly of polyaniline-grafted chitosan/glucose oxidase nanolayered films for electrochemical biosensor applications

  • Xin Hua Xu
  • Guang Lei RenEmail author
  • Juan Cheng
  • Qiang Liu
  • Dong Guang Li
  • Qiang Chen

Chitosan (CS), an N-deacetylated derivative of chitin, is a nature occurring biopolymer found in the exoskeleton of crustaceans, in fungal cell wall, and in other biological materials [1]. It has unusual combination properties [2], which includes excellent membrane-forming ability towards water, good adhesion, nontoxicity, high mechanical strength, especially good biocompatibility and susceptibility to chemical modification due to the presence of reactive amino and hydroxyl function groups. In recent years, chitosan was generally used to immobilize various enzymes. And we have reported the first attempt to prepare chitosan/glucose oxidase (GOD) nanolayered films for electrode modification by the technique of layer-by-layer (LBL) self-assembly [3]. It was found that the response current of the CS/GOD LBL films to glucose was improved since the amount of the immobilization enzyme increased with the increase of the layer number in a certain range. However, chitosan is nearly...


Chitosan Polyaniline Phosphate Buffer Solution Graft Copolymerization Multilayer Film 



We gratefully acknowledge Natural Science Foundation of Tianjin for financial support.


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Copyright information

© Springer Science+Business Media, LLC 2006

Authors and Affiliations

  • Xin Hua Xu
    • 1
  • Guang Lei Ren
    • 1
    Email author
  • Juan Cheng
    • 1
  • Qiang Liu
    • 1
  • Dong Guang Li
    • 1
  • Qiang Chen
    • 2
  1. 1.School of Materials Science and EngineeringTianjin UniversityTianjinPeople’s Republic of China
  2. 2.Life Sciences CollegeNankai UniversityTianjinPeople’s Republic of China

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