Interaction of pesticide pyroquilon with two different cucurbit[n]uril

  • Ying Fan
  • Ruihan Gao
  • Yangming Jiang
  • Bing Bian
  • Zhu TaoEmail author
  • Gang WeiEmail author
  • Xin XiaoEmail author
Original Article


In this work, we report a conceptual strategy for preventing pesticide degradation using cucurbit[n]uril to encapsulate pyroquilon (Pyn). The host–guest inclusion complexes of pyroquilon (Pyn) with CB[7] and CB[8] were prepared and characterized using 1H NMR spectroscopy, quadrupole-time of flight mass spectrometry (Q-TOF), isothermal titration calorimetry (ITC) and UV absorbance spectrophotometry. The experimental results revealed that the entire Pyn molecule resides within the cavities of CB[7] and CB[8], forming 1:1 inclusion complexes between CB[n] and Pyn. Our study on the release of Pyn demonstrated that CB[n]@Pyn exhibit sustained- and slow-release properties. Moreover, CB[8] can effectively shield UV irradiation and thereby protect the Pyn from photodegradation. Therefore, CB[7]@Pyn and CB[8]@Pyn have great potential to be used as slow-release agents.


Pyroquilon Cucurbit[7]uril Cucurbit[8]uril Inclusion complexes Release Antiphotolysis 



We acknowledge the support of the “Chun Hui” Project of the Chinese Ministry of Education (No. Z2017001), the Creative Research Groups of Guizhou Provincial Education Department (2017-028), the Science and Technology Program of Guizhou Province (No. 20185781), and the Innovation Program for High-level Talents of Guizhou Province (No. 2016-5657).

Supplementary material

10847_2019_936_MOESM1_ESM.doc (4.8 mb)
Supplementary material 1 (DOC 4935 kb)


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Copyright information

© Springer Nature B.V. 2019

Authors and Affiliations

  1. 1.State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of EducationGuizhou UniversityGuiyangPeople’s Republic of China
  2. 2.Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou ProvinceGuizhou UniversityGuiyangPeople’s Republic of China
  3. 3.State Key Laboratory of Functions and Applications of Medicinal PlantsGuizhou Medical UniversityGuiyangPeople’s Republic of China
  4. 4.College of Chemical and Environmental EngineeringShandong University of Science and TechnologyQingdaoPeople’s Republic of China
  5. 5.Commonwealth Scientific and Industrial Research Organization (CSIRO), ManufacturingLindfieldAustralia

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