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Successful embryo cryopreservation immediately following a full-term delivery in a woman with newly diagnosed Ewing’s sarcoma

  • Emma Giuliani
  • Erin M. Ellman
  • Rashmi Chugh
  • Molly B. MoravekEmail author
Fertility Preservation
  • 4 Downloads

Introduction

Ewing’s sarcoma is an aggressive, small blue round cell malignancy, affecting one per million people in the USA [1]. Albeit extremely rare, the incidence is much higher in children and young adults, a population who often have not completed their child-bearing. In fact, it accounts for approximately 10% of malignant bone cancers in children and young adults, and 3% of all childhood malignancies [1]. Unfortunately, 25% of patients who present with a clinically apparent localized tumor may also already have signs of occult metastatic disease [2]. Most commonly, metastases are found in the lungs, bones, and bone marrow [2].

While surgery remains a fundamental treatment strategy, the introduction of new chemotherapy agents and the combination of chemo and local radiotherapy (conformational RT and intensity-modulated RT) have led to increased 5-year survival rates from less than 15% to 65–70% for patients with localized disease and to 25–30% for those with metastatic disease [1...

Notes

Compliance with ethical standards

Informed consent was obtained from the patient described in this case report.

Conflict of interest

The authors declare that they have no conflict of interest.

References

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Emma Giuliani
    • 1
  • Erin M. Ellman
    • 1
  • Rashmi Chugh
    • 2
  • Molly B. Moravek
    • 1
    Email author
  1. 1.Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and GynecologyUniversity of MichiganAnn ArborUSA
  2. 2.Division of Hematology and Oncology, Department of Internal MedicineUniversity of MichiganAnn ArborUSA

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