Obstetrical complications of thin endometrium in assisted reproductive technologies: a systematic review

  • Youssef MouhayarEmail author
  • Jason M. Franasiak
  • Fady I. Sharara



The aim of the systematic review is to describe the obstetrical complications associated with pregnancies in the context of a thin endometrial lining.


Systematic review of the literature.


Patients who conceive in the setting of a thin endometrium have a significantly increased risk of early pregnancy loss, namely miscarriage and ectopic pregnancy. These patients also have a twofold increase in low birth weight and preterm delivery, as well as a significantly higher risk of intrauterine growth restriction and composite adverse perinatal outcomes.


In addition to the lower probability of conception, a thin endometrium in assisted reproductive technologies appears to be associated with both early and late pregnancy complications. These pregnancies thus warrant special attention and close follow-up from obstetricians.


Thin endometrium Obstetrical complications Miscarriage Ectopic pregnancy Low birth weight Preterm delivery 


Compliance with ethical standards

Institutional Review Board approval was not required since we only included published data.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of OB/GYNUniversity of Miami/Jackson Memorial HospitalMiamiUSA
  2. 2.IVI RMA New JerseyBasking RidgeUSA
  3. 3.Virginia Center for Reproductive MedicineRestonUSA
  4. 4.Department of OB/GYNGeorge Washington UniversityWashingtonUSA

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