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Journal of Autism and Developmental Disorders

, Volume 49, Issue 10, pp 4067–4078 | Cite as

The Empathizing–Systemizing Theory and ‘Extreme Male Brain’ (EMB) Theory in Parents of Children with Autism Spectrum Disorders (ASD): An Explorative, Cross-Sectional Study

  • Francesco Craig
  • Andrea De Giacomo
  • Rosa Savino
  • Marta Ruggiero
  • Luigi Russo
  • Isabella Fanizza
  • Lucia Margari
  • Antonio TrabaccaEmail author
Original Paper

Abstract

The aim of this study was to evaluate whether empathizing and systemizing are part of the parental broad autism phenotype (BAP). Parents (N = 76) of preschool children with a diagnosis of ASD and parents (N = 48) of typically developing (TD) children completed the Empathy Quotient (EQ) and Systemizing Quotient-Revised (SQ-R) questionnaires. The E–S discrepancy (D score) was used to test for sex differences in five “brain types”. Our results suggest that the E–S theory do not seem to be part of the BAP. However, a stronger drive to systemize than empathize (Type S brain) could be a highly inheritable cognitive endophenotype of mothers of children with ASD. This study should be repeated with a larger sample size.

Keywords

Autism spectrum disorder Parental broad autism phenotype Empathizing Systemizing Extreme male brain theory 

Notes

Author Contributions

FC conceived of the study, participated in its design and coordination and drafted the manuscript; AD participated in the design and interpretation of the data; RS participated in the design and interpretation of the data; MR participated in the design and coordination of the study and performed the measurement; LR participated in the design of the study and performed the statistical analysis; IF participated in the design and coordination of the study and performed the measurement; LM participated in its design and coordination and helped to draft the manuscript; AT conceived of the study, and helped to draft the manuscript.

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Francesco Craig
    • 1
  • Andrea De Giacomo
    • 2
  • Rosa Savino
    • 1
  • Marta Ruggiero
    • 1
  • Luigi Russo
    • 1
  • Isabella Fanizza
    • 1
  • Lucia Margari
    • 2
  • Antonio Trabacca
    • 1
    Email author
  1. 1.Unit for Severe Disabilities in Developmental Age and Young AdultsScientific Institute, IRCCSBrindisiItaly
  2. 2.Child Neuropsychiatry Unit, Department of Basic Medical Sciences, Neuroscience and Sense OrgansUniversity of Bari “Aldo Moro”BariItaly

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