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Fifteen-Year Prospective Follow-Up Study of Adult Outcomes of Autism Spectrum Disorders Among Children Attending Centers in Five Regional Departments in France: The EpiTED Cohort

  • Amaria BaghdadliEmail author
  • Cécile Rattaz
  • Cécile Michelon
  • Eric Pernon
  • Kerim Munir
OriginalPaper

Abstract

There is limited data on long-term outcome of ASD with co-occurring intellectual disabilities (ID) and challenging behaviours in France. The EpiTED period cohort is a 15 years longitudinal study of the developmental trajectories of 281 children initially recruited at mean age of 5 years. Two contrasted developmental trajectories were identified. Low cognitive level, absence of language, and higher ASD scores at baseline were predictive of low growth at follow-up. As adults the participants were predisposed to persistent co-occurring challenging behaviours as well as underlying ID impacting their ability to function independently. The results underscore the need for development of services and supports for adults with ASD in France who may also have already lacked access to adequate interventions and support services.

Keywords

Autism spectrum disorders Cohort Longitudinal Long-term follow-up France 

Notes

Acknowledgments

We wish to sincerely thank the participants and their families for their valuable and long-lasting collaboration and their confidence in our study. We also extend our thanks to the research teams for their support during the past 15 years. A special thought to Florine Dellapiazza and to Colette Boy for their help with the literature review.

Author Contributions

AB was involved in the study design and methods, data collection, interpretation of results, writing, and revision of the initial draft. EP was involved in the study design and methods and data collection. CM and CR were involved in data analysis, interpretation of results, writing, and revision of the draft. KM was involved in the interpretation, writing, and revision of the draft. All the authors have critically revised this article and approved the final version to be published.

Funding

This work was supported by grants from the Orange Foundation, and the French national health institute (PHRC 1997 & 2007 and ANR Blanc).

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Approval

This study was approved by the Medical ethical committee and the National Commission for Computing and Liberties (CNIL. number 1585321 v0).

Informed Consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Département de PsychiatrieCentre Universitaire Hospitalier (CHU) de MontpellierMontpellierFrance
  2. 2.Centre de Ressources Autisme Languedoc-RoussillonCHU MontpellierMontpellierFrance
  3. 3.Centre de Recherche en Épidémiologie et Santé des Populations, U1178, INSERMParisFrance
  4. 4.Ecole de MédecineUniversité de MontpellierMontpellierFrance
  5. 5.Developmental Medicine Center, Boston Children’s HospitalHarvard Medical SchoolBostonUSA

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