Journal of Autism and Developmental Disorders

, Volume 49, Issue 1, pp 185–196 | Cite as

Reliability and Validity of the Chinese Version of Modified Checklist for Autism in Toddlers, Revised, with Follow-Up (M-CHAT-R/F)

  • Cuihua Guo
  • Meifang Luo
  • Xuxiang Wang
  • Saijun Huang
  • Zhaoxue Meng
  • Jie Shao
  • Xuan Zhang
  • Zhi Shao
  • Jieling Wu
  • Diana L. RobinsEmail author
  • Jin JingEmail author
Original Paper


Although early detection of autism facilitates intervention, early detection strategies are not yet widespread in China. To improve the situation, the Chinese version of the Modified Checklist for Autism in Toddlers, Revised with Follow-Up (M-CHAT-R/F) was validated. The sample included 7928 toddlers, aged 16 to 30 months, screened during their routine care in six provinces of China. When the cut-off value was 3, the sensitivity and specificity of M-CHAT-R were 0.963 and 0.865. The inter-rater reliability and the test–retest reliability were also adequate (intraclass correlation coefficients were 0.853 and 0.759, both ps < .01). The Chinese version of M-CHAT-R/F is an effective tool for early detection of ASD and is applicable to early screening in China.


Autism spectrum disorder Early screening Modified Checklist for Autism in Toddlers Revised with Follow-Up (M-CHAT-R/F) China 



This study is supported by the National Natural Science Foundation of China (Grant No. 81573169) and a Grant from the Shenzhen Xinzhi Institute of Psychological Assessment Technology (Grant No. 5100071020274). We would like to thank the following groups: (1) Pediatricians, psychotherapists and health care providers for participating this study: Li Rongping, Li Xinting, Su Xi, YuHong, Zhang Yaru, Fan Xin, Ning Jing, Xiao Yu, Liang Deyi, Luo Yan, Xu Haiqing, Xu Lin, Yu Hong, Yao Xue. (2) All of the members of the research team who participated in data collection. (3) All of the parents and toddlers for their participation and support in this study.

Author Contributions

CG conceived of the study, participated in its design and coordination and drafted the manuscript; ML and XW participated in the design of the study and performed the statistical analysis; SH, ZXM, JS, XZ, ZS and JW participated in the design and coordination of the study and performed the measurement; DLR and JJ conceived of the study, and participated in its design and coordination and helped to draft the manuscript. All authors read and approved the final manuscript.

Compliance with Ethical Standards

Conflict of interest

Diana L. Robins is co-owner of M-CHAT, LLC, which licenses use of M-CHAT and related materials in commercial products. There were no royalties from the use of M-CHAT-R/F in the current study. All other authors report no conflicts of interest.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Cuihua Guo
    • 1
  • Meifang Luo
    • 1
  • Xuxiang Wang
    • 1
  • Saijun Huang
    • 2
  • Zhaoxue Meng
    • 3
  • Jie Shao
    • 4
  • Xuan Zhang
    • 5
  • Zhi Shao
    • 6
  • Jieling Wu
    • 7
  • Diana L. Robins
    • 8
    Email author
  • Jin Jing
    • 1
    Email author
  1. 1.Department of Maternal and Child Health, School of Public HealthSun Yat-sen UniversityYuexiuPeople’s Republic of China
  2. 2.Southern Medical University Affiliated Maternal & Child Health Hospital of FoshanFoshanPeople’s Republic of China
  3. 3.Tongzhou Maternal&Child Health Hospital of BeijingBeijingPeople’s Republic of China
  4. 4.The Children’s Hospital, Zhejiang University School of MedicineHangzhouPeople’s Republic of China
  5. 5.Department of Child Health CareHubei Maternal and Child Health HospitalWuhanPeople’s Republic of China
  6. 6.The Ninth People’s Hospital of ChongqingBeibeiPeople’s Republic of China
  7. 7.Guangdong Women and Children HospitalGuangzhouPeople’s Republic of China
  8. 8.AJ Drexel Autism InstituteDrexel UniversityPhiladelphiaUSA

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