International Ophthalmology

, Volume 39, Issue 11, pp 2649–2659 | Cite as

Ocular inflammation associated with relapsing polychondritis in Japanese patients: a review of 11 patients

  • Rie TanakaEmail author
  • Toshikatsu Kaburaki
  • Hisae Nakahara
  • Keiko Komae
Original Paper



To investigate the clinical features of patients with ocular inflammation associated with relapsing polychondritis in Japan.


Ocular findings, systemic symptoms, and therapies were analysed retrospectively.


Nine of 11 patients had scleritis (diffuse scleritis: six patients, posterior scleritis: two patients, episcleritis: one patient) and two patients had anterior uveitis. All cases were bilateral, and ten patients experienced recurrent episodes. Auricular chondritis was the most common systemic symptom. Ten patients were administered systemic steroids, and five patients were administered other immunosuppressive medications for severe systemic symptoms. At their last visit, none of the patients had decreased visual acuity that resulted from relapsing polychondritis-associated ocular inflammation.


Ocular inflammation is often bilateral and recurring. Patients with ocular inflammation must be questioned regarding systemic symptoms so that the signs of relapsing polychondritis are not overlooked. Early diagnosis and prompt, appropriate treatment are important because relapsing polychondritis is a potentially lethal disease.


Ocular inflammation Relapsing polychondritis Scleritis Treatment Uveitis 



This work was supported by JSPS KAKENHI Grant Number JP 16K11281.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Human and animal rights

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.


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Copyright information

© Springer Nature B.V. 2019

Authors and Affiliations

  1. 1.Department of OphthalmologyThe University of Tokyo HospitalTokyoJapan

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