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International Ophthalmology

, Volume 39, Issue 9, pp 2033–2040 | Cite as

Anterior chamber indices in a population-based study using the Pentacam

  • Hassan Hashemi
  • AbbasAli Yekta
  • Farzad Khodamoradi
  • Mohamadreza Aghamirsalim
  • Amir Asharlous
  • Mehrdad Assadpour
  • Mehdi KhabazkhoobEmail author
Original Paper
  • 74 Downloads

Abstract

Purpose

To determine the distribution of anterior chamber depth (ACD), anterior chamber volume (ACV), and anterior chamber angle (ACA) values in a rural population over 5 years of age using the Pentacam.

Methods

In this cross-sectional study, samples were selected from over 1-year-old inhabitants of two villages in Iran using a multistage cluster sampling approach. All participants underwent the measurement of uncorrected and corrected visual acuity and auto-refraction, retinoscopy, subjective refraction, and slit lamp examination. Finally, corneal imaging was done for all subjects over 5 years of age using the Pentacam.

Results

Of 3851 selected individuals, 3314 participated in the study, of whom 2681 met the inclusion criteria. The mean age of the sample was 36.03 ± 18.5 years (range 6–90 years). The mean ACD, ACA, and ACV values were 3.37 mm (95% CI: 3.37–3.39), 34.82° (95% CI: 34.45–35.2), and 159.17 µL (95% CI: 156–161.36), respectively. The results of multiple linear regression models showed that ACD, ACA, and ACV values reduced with age, and ACD and ACV values were significantly higher in males. ACA and ACV values correlated inversely with central corneal thickness, while the ACA value correlated directly with keratometry and inversely with the ACV value.

Conclusion

This study is one of the few studies in the world showing changes in ACD values in different age groups using the Pentacam. According to the results, aging was associated with a decline in the mean ACD, ACA, and ACV values. These parameters were the largest in patients with emmetropia and smallest in hyperopic subjects.

Keywords

Anterior chamber depth Anterior chamber volume Anterior chamber angle Cross-sectional study Distribution 

Notes

Funding

This project was supported by Deputy of Research of Shahid Beheshti University of Medical Sciences, the Iran.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

References

  1. 1.
    Cho HK, Kee C (2014) Population-based glaucoma prevalence studies in Asians. Surv Ophthalmol 59:434–447.  https://doi.org/10.1016/j.survophthal.2013.09.003 CrossRefGoogle Scholar
  2. 2.
    Tham YC, Li X, Wong TY et al (2014) Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology 121:2081–2090.  https://doi.org/10.1016/j.ophtha.2014.05.013 CrossRefGoogle Scholar
  3. 3.
    Wright C, Tawfik MA, Waisbourd M et al (2016) Primary angle-closure glaucoma: an update. Acta Ophthalmol 94:217–225.  https://doi.org/10.1111/aos.12784 CrossRefGoogle Scholar
  4. 4.
    Congdon NG, Spaeth GL, Augsburger J et al (1999) A proposed simple method for measurement in the anterior chamber angle: biometric gonioscopy. Ophthalmology 106:2161–2167.  https://doi.org/10.1016/s0161-6420(99)90499-2 CrossRefGoogle Scholar
  5. 5.
    Yi JH, Hong S, Seong GJ et al (2008) Anterior chamber measurements by Pentacam and AS-OCT in eyes with normal open angles. Korean J Ophthalmol 22:242–245.  https://doi.org/10.3341/kjo.2008.22.4.242 CrossRefGoogle Scholar
  6. 6.
    Barrett BT, McGraw PV, Murray LA et al (1996) Anterior chamber depth measurement in clinical practice. Optom Vis Sci 73:482–486CrossRefGoogle Scholar
  7. 7.
    Hashemi H, Khabazkhoob M, Mohazzab-Torabi S et al (2016) Anterior chamber angle and anterior chamber volume in a 40- to 64-year-old population. Eye Contact Lens 42:244–249.  https://doi.org/10.1097/icl.0000000000000192 CrossRefGoogle Scholar
  8. 8.
    Dinc UA, Gorgun E, Oncel B et al (2010) Assessment of anterior chamber depth using Visante optical coherence tomography, slitlamp optical coherence tomography, IOL Master, Pentacam and Orbscan IIz. Ophthalmologica 224:341–346.  https://doi.org/10.1159/000313815 CrossRefGoogle Scholar
  9. 9.
    Ucakhan OO, Ozkan M, Kanpolat A (2009) Anterior chamber parameters measured by the Pentacam CES after uneventful phacoemulsification in normotensive eyes. Acta Ophthalmol 87:544–548.  https://doi.org/10.1111/j.1755-3768.2008.01305.x CrossRefGoogle Scholar
  10. 10.
    Nemeth G, Vajas A, Kolozsvari B et al (2006) Anterior chamber depth measurements in phakic and pseudophakic eyes: Pentacam versus ultrasound device. J Cataract Refract Surg 32:1331–1335.  https://doi.org/10.1016/j.jcrs.2006.02.057 CrossRefGoogle Scholar
  11. 11.
    He M, Huang W, Zheng Y et al (2008) Anterior chamber depth in elderly Chinese: the Liwan eye study. Ophthalmology 115:1286–1290.  https://doi.org/10.1016/j.ophtha.2007.12.003 CrossRefGoogle Scholar
  12. 12.
    Rabsilber TM, Khoramnia R, Auffarth GU (2006) Anterior chamber measurements using Pentacam rotating Scheimpflug camera. J Cataract Refract Surg 32:456–459.  https://doi.org/10.1016/j.jcrs.2005.12.103 CrossRefGoogle Scholar
  13. 13.
    Cheon MH, Sung KR, Choi EH et al (2010) Effect of age on anterior chamber angle configuration in Asians determined by anterior segment optical coherence tomography; clinic-based study. Acta Ophthalmol 88:e205–e210.  https://doi.org/10.1111/j.1755-3768.2010.01960.x CrossRefGoogle Scholar
  14. 14.
    Sun JH, Sung KR, Yun SC et al (2012) Factors associated with anterior chamber narrowing with age: an optical coherence tomography study. Invest Ophthalmol Vis Sci 53:2607–2610.  https://doi.org/10.1167/iovs.11-9359 CrossRefGoogle Scholar
  15. 15.
    Richdale K, Bullimore MA, Zadnik K (2008) Lens thickness with age and accommodation by optical coherence tomography. Ophthalmic Physiol Opt 28:441–447.  https://doi.org/10.1111/j.1475-1313.2008.00594.x CrossRefGoogle Scholar
  16. 16.
    Wendt M, Croft MA, McDonald J et al (2008) Lens diameter and thickness as a function of age and pharmacologically stimulated accommodation in rhesus monkeys. Exp Eye Res 86:746–752.  https://doi.org/10.1016/j.exer.2008.01.022 CrossRefGoogle Scholar
  17. 17.
    Xu L, Cao WF, Wang YX et al (2008) Anterior chamber depth and chamber angle and their associations with ocular and general parameters: the Beijing Eye Study. Am J Ophthalmol 145:929–936.  https://doi.org/10.1016/j.ajo.2008.01.004 CrossRefGoogle Scholar
  18. 18.
    Fontana ST, Brubaker RF (1980) Volume and depth of the anterior chamber in the normal aging human eye. Arch Ophthalmol 98:1803–1808CrossRefGoogle Scholar
  19. 19.
    Ulvik SO, Seland JH, Wentzel-Larsen T (2005) Refraction, axial length and age-related maculopathy. Acta Ophthalmol Scand 83:419–423.  https://doi.org/10.1111/j.1395-3907.2005.520_corr.x CrossRefGoogle Scholar
  20. 20.
    Roy A, Kar M, Mandal D et al (2015) Variation of axial ocular dimensions with age, sex, height, BMI-and their relation to refractive status. J Clin Diagn Res 9:01–04.  https://doi.org/10.7860/jcdr/2015/10555.5445 CrossRefGoogle Scholar
  21. 21.
    Maeng H-SRE, Chung T-Y, Chung E-S (2010) Effects of anterior chamber depth and axial length on refractive error after intraocular lens implantation. J Korean Ophthalmol Soc 51:195–202CrossRefGoogle Scholar
  22. 22.
    Muller M, Dahmen G, Porksen E et al (2006) Anterior chamber angle measurement with optical coherence tomography: intraobserver and interobserver variability. J Cataract Refract Surg 32:1803–1808.  https://doi.org/10.1016/j.jcrs.2006.07.014 CrossRefGoogle Scholar
  23. 23.
    Wu RY, Nongpiur ME, He MG et al (2011) Association of narrow angles with anterior chamber area and volume measured with anterior-segment optical coherence tomography. Arch Ophthalmol 129:569–574.  https://doi.org/10.1001/archophthalmol.2011.68 CrossRefGoogle Scholar
  24. 24.
    Sorbara L, Maram J, Fonn D et al (2010) Metrics of the normal cornea: anterior segment imaging with the Visante OCT. Clin Exp Optom 93:150–156.  https://doi.org/10.1111/j.1444-0938.2010.00472.x CrossRefGoogle Scholar
  25. 25.
    Emre S, Doganay S, Yologlu S (2007) Evaluation of anterior segment parameters in keratoconic eyes measured with the Pentacam system. J Cataract Refract Surg 33:1708–1712.  https://doi.org/10.1016/j.jcrs.2007.06.020 CrossRefGoogle Scholar
  26. 26.
    Oh YG, Minelli S, Spaeth GL et al (1994) The anterior chamber angle is different in different racial groups: a gonioscopic study. Eye (Lond) 8(Pt 1):104–108.  https://doi.org/10.1038/eye.1994.20 CrossRefGoogle Scholar
  27. 27.
    Olsen T (2006) Prediction of the effective postoperative (intraocular lens) anterior chamber depth. J Cataract Refract Surg 32:419–424.  https://doi.org/10.1016/j.jcrs.2005.12.139 CrossRefGoogle Scholar
  28. 28.
    Labiris G, Gkika M, Katsanos A et al (2009) Anterior chamber volume measurements with Visante optical coherence tomography and Pentacam: repeatability and level of agreement. Clin Exp Ophthalmol 37:772–774.  https://doi.org/10.1111/j.1442-9071.2009.02132.x CrossRefGoogle Scholar
  29. 29.
    Dinc U, Oncel B, Gorgun E et al (2009) Quantitative assessment of anterior chamber volume using slit-lamp OCT and Pentacam. Eur J Ophthalmol 19:411–415CrossRefGoogle Scholar
  30. 30.
    Salouti R, Nowroozzadeh MH, Zamani M et al (2010) Comparison of anterior chamber depth measurements using Galilei, HR Pentacam, and Orbscan II. Optomet J Am Optomet Assoc 81:35–39.  https://doi.org/10.1016/j.optm.2009.04.100 CrossRefGoogle Scholar
  31. 31.
    Auffarth GU, Tetz MR, Biazid Y et al (1997) Measuring anterior chamber depth with Orbscan Topography System. J Cataract Refract Surg 23:1351–1355CrossRefGoogle Scholar
  32. 32.
    Lackner B, Schmidinger G, Skorpik C (2005) Validity and repeatability of anterior chamber depth measurements with Pentacam and Orbscan. Optom Vis Sci 82:858–861CrossRefGoogle Scholar
  33. 33.
    Hashemi H, Khabazkhoob M, Miraftab M et al (2012) The distribution of axial length, anterior chamber depth, lens thickness, and vitreous chamber depth in an adult population of Shahroud, Iran. BMC Ophthalmol 12:50CrossRefGoogle Scholar

Copyright information

© Springer Nature B.V. 2018

Authors and Affiliations

  1. 1.Noor Research Center for Ophthalmic EpidemiologyNoor Eye HospitalTehranIran
  2. 2.Refractive Errors Research CenterMashhad University of Medical SciencesMashhadIran
  3. 3.Noor Ophthalmology Research CenterNoor Eye HospitalTehranIran
  4. 4.Eye Research Center, Rassoul Akram HospitalIran University of Medical SciencesTehranIran
  5. 5.Department of Medical Surgical Nursing, School of Nursing and MidwiferyShahid Beheshti University of Medical SciencesTehranIran

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