Three-dimensional surface presentation of optic nerve head from SPECTRALIS OCT images: observing glaucoma patients
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To propose an innovative three-dimensional surface presentation of the optic nerve head (ONH) from the SPECTRALIS optical coherence tomography (OCT) device.
A dataset of OCT ONH files from eight glaucoma follow-up patients was obtained. The set consisted of OCT ONH images for 20 right eyes (OD) and 17 left eyes (OS). Preprocessing steps followed with OCT reconstruction procedures were designed. The three-dimensional (3D) surface rendering was generated for all OCT ONH images. A set of eight International Organization for Standardization (ISO) roughness parameters were calculated to assess the disparities in the 3D ONH surface morphology during follow-up visit.
The 3D ONH surface presents a new OCT display to ophthalmology; so, the physician can examine the surface morphology of the OCT ONH region. The 3D ONH surface’s shape varied noticeably during follow-up visits in glaucoma patients. The percentage disparity of ONH surface roughness’s can be as small as 3% or almost zero, but it can be as large as 56% or 100%.
The approximation of OCT ONH 3D surface is feasible; it may possibly be beneficial to ophthalmology. It allows ophthalmologist to perceive the entire changes in the ONH surface morphology during the follow-up attendances; so, it can be used to observe patient health. The ISO roughness measurements are suggestive complementary factors to observe the alterations in the OCT ONH region.
KeywordsOptical coherence tomography Optic nerve head 3D surface visualization Glaucoma
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
The subjects in this experiment are retrospective OCT studies. The identifications of patients were removed from all patient’s OCT files so they become anonymous OCT files.
- 3.Gelikonov VM, Gelikonov GV, Dolin LS, Kamensky VA, Sergeev AM, Shakhova NM, Galdkova ND, Zagaynova EV (2003) Optical coherence tomography: physical principles and applications. Laser Phys 13:692–702Google Scholar
- 17.ISO 4287:2000 Geometrical product specification (GPS)—Surface texture. Profile method. Terms, definitions and surface texture parametersGoogle Scholar
- 18.ISO 25178-2:2012 Geometrical product specifications (GPS) - Surface texture: areal - Part 2: terms, definitions and surface texture parametersGoogle Scholar
- 19.Yousefi S, Goldbaum MH, Balasubramanian M, Jung T, Weinreb RN, Medeiros FA, Zangwill LM, Liebmann JM, Girkin CA, Bowd C (2013) Glaucoma progression detection using structural retinal nerve fiber layer measurements and functional visual field points. IEEE Trans Biomed Eng 00:1–12Google Scholar
- 20.Koprowski R, Rzendkowski M, Wróbel Z (2014) Automatic method of analysis of OCT images in assessing the severity degree of glaucoma and the visual field loss. BioMed Eng (Online) https://doi.org/10.1186/1475-925x-13-16