International Ophthalmology

, Volume 39, Issue 4, pp 929–934 | Cite as

Intraoperative optical coherence tomography in the full-thickness macular hole surgery with internal limiting membrane inverted flap placement

  • Enrico BorrelliEmail author
  • Michele Palmieri
  • Agbeanda Aharrh-Gnama
  • Vincenzo Ciciarelli
  • Rodolfo Mastropasqua
  • Paolo Carpineto
Case Report



To describe the helpfulness of using intraoperative optical coherence tomography (OCT) during surgery for full-thickness macular hole (FTMH).


This observational case series identifies three patients with FTMH who were treated with vitrectomy, internal limiting membrane (ILM) peel with inverted ILM flap, which was tucked into the MH, and air with 18% Sulfur Hexafluoride (SF6) gas tamponade. Intraoperative OCT was used to confirm positioning of the ILM flap, even after complete air-fluid exchange. The patients were followed for three months after surgery and all reached a good morphological and functional outcome.


If confirmed by a prospective longitudinal study, the intraoperative OCT might become an important tool in assisting FTMH surgery.


Intraoperative OCT Full-thickness macular hole Vitrectomy ILM peeling ILM flap 


Compliance with ethical standards

Conflict of interest

All the authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer Science+Business Media B.V., part of Springer Nature 2018

Authors and Affiliations

  1. 1.Ophthalmology Clinic, Department of Medicine and Science of AgeingUniversity G. D’Annunzio Chieti-PescaraChietiItaly
  2. 2.Ophthalmology ClinicUniversity of MarcheAnconaItaly

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