International Ophthalmology

, Volume 39, Issue 4, pp 935–941 | Cite as

Mirror image of familial exudative vitreoretinopathy in identical twins

  • Mehmet Yasin TekeEmail author
  • Kemal Tekin
  • Emre Aydemir
  • Fuat Yavrum
Case Report



To report the identical twins who had mirror fundus and angiographic images of familial exudative vitreoretinopathy (FEVR).

Case presentation

A pair of 16 year old female twins presented with mirror-image asymmetry of monocular decreased vision. The twins were born full term with normal weights. Neither twin revealed any medical disorders during childhood and there was no known family history of ocular disorders. On ocular examination, the best corrected visual acuity (BCVA) was 20/20 in OD and 20/63 in OS for twin 1. For the twin 2, the BCVAs were 20/63 and 20/20 for OD and OS, respectively. Intraocular pressures were within normal limits and anterior segment examinations were unremarkable for both twins. Dilated fundus examinations and angiographic images revealed characteristics FEVR appearance with mirror image phenomenon in the twins.


This is the first report describing identical twins with mirror images of FEVR. This report may confirm a strong underlying genetic inheritance in the pathogenesis of FEVR.


Familial exudative vitreoretinopathy Identical twins Mirror-image phenomenon 


Compliance with ethical standards

Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest or non-financial interest in the subject matter or materials discussed in this paper.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all participants included in the paper.


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Copyright information

© Springer Science+Business Media B.V., part of Springer Nature 2018

Authors and Affiliations

  • Mehmet Yasin Teke
    • 1
    Email author
  • Kemal Tekin
    • 2
  • Emre Aydemir
    • 3
  • Fuat Yavrum
    • 3
  1. 1.Department of Retinal DiseasesAnkara Ulucanlar Eye Training and Research HospitalAnkaraTurkey
  2. 2.Ophthalmology DepartmentKars State HospitalKarsTurkey
  3. 3.Ankara Ulucanlar Eye Training and Research HospitalAnkaraTurkey

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