In the Thick of It: The Many Faces of Collagenous Gastritis

  • Sundeep SinghEmail author
  • Emily Jing
  • Jeanne Shen
Stanford Multidisciplinary Seminars

Case Presentations and Evolution

Case 1

A 45-year-old Caucasian woman with no significant past medical history was initially evaluated in the emergency department for complaints of several months of intermittent epigastric discomfort, followed by 3 days of melena. She denied any long-term NSAID use, nausea, vomiting, early satiety, or weight loss. Upon initial evaluation, laboratory investigations revealed microcytic anemia with hematocrit 24%, MCV 78 fL, platelets 281,000 K/uL, WBC 5.9 K/µL, and INR 1.08. Her renal function and liver function tests were normal.

Esophagogastroduodenoscopy (EGD) revealed a normal esophagus, a nodular gastric body, but otherwise normal stomach and duodenal mucosa. Four biopsies were taken from the gastric body; histopathology showed moderate mixed chronic inflammation of the lamina propria, a mild increase in eosinophils, and thickening of the subepithelial collagen layer in areas of erosions (Fig.  1). Testing for Helicobacter pyloriwas negative....



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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2020

Authors and Affiliations

  1. 1.StanfordUSA
  2. 2.Walnut CreekUSA

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