Colonic Perforation as Initial Presentation of Amyloid Disease: Case Report and Literature Review
Amyloidosis is an uncommon disease caused by the deposition of amyloid fibrils in tissues. This disease does not usually require surgical intervention, which could be warranted in the presence of complications such as bleeding, obstruction, or perforation. We present a case of primary amyloidosis of the colon in a patient affected by polymyositis who underwent Hartmann’s procedure after a spontaneous colonic perforation. After 2 months of well-being, the patient underwent two consecutive surgical procedures for stenosis of the ostomy orifice.
A review of the literature has been performed, gathering case reports highlighting the distribution of this disease by age, gender, location, and treatment when available.
Gastrointestinal amyloid disease is a rare condition, and it could be considered among the rare causes of intestinal perforation. Timely surgical management is often necessary.
KeywordsAmyloid disease Perforation Surgery
Past medical history
Hepatitis C virus
Compliance with Ethical Standards
Conflict of interest
None of the authors have any conflicts of interest pertaining to this work.
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