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Digestive Diseases and Sciences

, Volume 64, Issue 10, pp 2911–2922 | Cite as

Clinical Efficiency and Safety of Magnetic-Controlled Capsule Endoscopy for Gastric Diseases in Aging Patients: Our Preliminary Experience

  • Shaoheng Zhang
  • Tao Sun
  • Yue Xie
  • Changhui Yu
  • Shaoqin Jin
  • Jianlin Yu
  • Hua MaoEmail author
Original Article
  • 78 Downloads

Abstract

Background

The elderly assess higher incidence of gastric diseases and may meet challenges and contraindications when flexible esophagogastroduodenoscopy intubating. Magnetic-controlled capsule endoscopy (MCE) is declared as a promising alternative, but its applications in elderly population do not attach enough importance.

Aims

To explore MCE’s efficiency and safety in the elderly.

Methods

A single-center retrospective study has been conducted. Data from the elderly group (>65 year-old) who underwent MCE examination, including indications, MCE outcomes, gastric conditions, evaluations from MCE manipulators and endoscopists, subjective discomforts, adverse events, etc., had been collected, then analyzed, and compared with the ones from the middle-aged group (>40, ≤ 65 year-old).

Results

During April 2015 and September 2018, 98 elderly patients and 72 middle-aged patients underwent MCE examination. In the elderly, the indications included poor physical condition (28.6%), severe angiocardiopathy (39.8%), EGD rejection (13.3%), severe respiratory disorder (8.2%), craniocerebral injury (8.2%), and allergy to anesthetics (2.0%). Rate of complete gastric observation and positive finding were 98.0% and 72.4% (vs. middle-aged group, 94.4%, 56.9%, P = 0.220, 0.035), and gastric conditions showed relatively inferior. Gastric preparation and MCE procedure were generally tolerated, but three elderly patients (3.1%) experienced capsule blockage in stomach.

Conclusions

Our preliminary data support that MCE offers considerable benefit and is general safe for the elderly. We hope such data promote greater awareness of innovative attempts for the specific elderly, and expect multi-center, large-scale trials with randomized controlled design bring optimized strategies for better gastric visibility, efficacy and lower potential risk.

Keywords

Magnetic-controlled capsule endoscopy The elderly Gastric disease Diagnostic efficiency Safety evaluation 

Abbreviations

MCE

Magnetic-controlled capsule endoscopy

GDs

Gastric diseases

EGD

Esophagogastroduodenoscopy

VCE

Video capsule endoscopy

CE

Capsule endoscopy

GI

Gastrointestinal

SCD

Severe cardiovascular disease

SRD

Severe respiratory disease

COPD

Chronic obstructive pulmonary disease

Notes

Acknowledgments

The authors thank the colleagues, including Y Xie, SQ Jin, PZ Su, Tao Sun, Changhui Yu, and Jianlin Yu, for effective assistances on study design, MCE manipulation, retrospectively evaluation.

Author’s contribution

SH Zhang and H Mao were involved in conception and design; SH Zhang, Y Xie, SQ Jin, T Sun, CH Yu, and JL Yu contributed to analysis and interpretation of the data; SH Zhang drafted the article; T Sun, CH Yu, JL Yu, and H Mao were involved in critical revision of the article for important intellectual content; SH Zhang and H Mao approved the final version of the manuscript.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Gastroenterology, Zhujiang HospitalSouthern Medical UniversityGuangzhouChina

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