Risk of Rebleeding After Hemostasis for Peptic Ulcer
The important observation by Kondo et al.  reports the high risk of rebleeding after hemostasis of peptic ulcer. They analyze the risk factors and find that a high dose of steroids is an important one . We concur; however, we believe a further risk factor should also be analyzed, i.e., the presence or not of Helicobacter pylori infection; indeed, Asaka et al.  reported a 66% rate of rebleeding due to peptic ulcer (PU) in Japanese patients who failed to eradicate this bacterium. We and others in Italy found that rebleeding was very rare after successful cure of H. pylori [3, 4]. One important observation is that during the acute phase of PU bleeding very often gastric biopsies lead to a false negative for the presence of H. pylori, as clearly stated by the Maastricht V/Florence consensus report . This observation highlights the need for multiple tests for the detection of this bacterium in all patients, but more so in the bleeding ones . Recently, Takatori et...
AP conceived the writing, and all authors contributed to the completion and approval of the letter.
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Conflict of interest
The authors declare that they have no conflict of interest.
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