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Digestive Diseases and Sciences

, Volume 64, Issue 2, pp 524–531 | Cite as

Endoscopic Enucleation Is Effective and Relatively Safe in Small Gastric Subepithelial Tumors Originating from Muscularis Propria

  • Eun Jung Ko
  • Byoung Wook Bang
  • Kye Sook Kwon
  • Yong Woon Shin
  • Hyung Kil KimEmail author
Original Article
  • 61 Downloads

Abstract

Background

Gastric subepithelial tumors originating from muscularis propria (MP) are usually benign, but some have malignant potential.

Aims

The aim of this study was to evaluate the utility of endoscopic enucleation for the diagnosis and treatment of MP tumors.

Patients and Methods

From January 2010 to February 2018, eighty patients with gastric MP tumors underwent endoscopic enucleation at our hospital. Band ligation and resection (BLR) or endoscopic muscularis resection (EMD) was performed based on considerations of tumor size (≤ 12 mm or > 12 mm). Tumor characteristics, procedure times, complete resection rates, adverse events and recurrence were analyzed.

Results

Eighty patients with 82 lesions were eligible for inclusion in this study. BLR was used to treat 41 lesions. For these lesions, mean tumor size was 9.5 mm, median procedural time was 17.6 min (range 4–52), and the endoscopic complete resection rate was 100% (41/41). Perforation was developed in four patients, and was closed by endoscopic clipping. EMD was used to treat 41 lesions. Median procedure time was 66.1 min (range 12–260) and the endoscopic complete resection rate was 85.4% (35/41). Perforation occurred in eight patients, four patients received endoscopic treatment and four underwent surgery. Tumor recurrence was not observed in any patient over follow-up (mean 26.3 months).

Conclusion

Endoscopic enucleation appears to offer an effective, relatively safe means for diagnosing and treating gastric subepithelial tumors originating from the MP, and BLR provides a straightforward, effective, and relatively safe treatment for small MP tumors (≤ 12 mm).

Keywords

Stomach neoplasms Gastrointestinal stromal tumors Leiomyoma Endoscopy 

Notes

Authors’ contribution

Eun Jung Ko and Byoung Wook Bang made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data. Kye Sook Kwon and Yong Woon Shin made substantial contribution to acquisition of data. Hyung Kil Kim has been involved in drafting the manuscript or revising it critically for important intellectual content.

Funding

This work was supported by Inha University Research Grant (2017).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no competing interests.

Ethics approval and consent to participate

This was a retrospective study. Informed consent was obtained from all patients before the procedure, and this study was approved by the institutional review board of Inha University Hospital. (2014-01-102).

Availability of data and materials

The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Eun Jung Ko
    • 1
  • Byoung Wook Bang
    • 1
  • Kye Sook Kwon
    • 1
  • Yong Woon Shin
    • 1
  • Hyung Kil Kim
    • 1
    Email author
  1. 1.Division of Gastroenterology, Department of Internal MedicineInha University College of Medicine, Inha University HospitalIncheonRepublic of Korea

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