Duodenitis, Diarrhea, and Death in a Patient with AIDS
A 47-year-old Native American male was initially evaluated in the emergency room with a 4-month history of diarrhea, which was described as voluminous, foul smelling, and occurring 3–6 times daily, both day and night. It was associated with diminished oral intake, lassitude, anorexia, and an unintentional weight loss of 42 lb over the past year. His roommate additionally reported that, following the diagnosis of infection with human immunodeficiency virus (HIV), the patient had become disoriented, forgetful, and anhedonic.
The patient’s HIV infection was diagnosed 8 months prior to this presentation. At the time of diagnosis, he was diagnosed with pneumococcal pneumonia and hairy leukoplakia as complications of the acquired immune deficiency syndrome (AIDS). The major risk factor was having unprotected sex with men. The patient’s cluster of differentiation (CD)4 count at the time of diagnosis was 12 cells/mm3, and his viral load was 271,000 copies/ml. After hospital...
KeywordsHIV AIDS Mycobacterium avium Diarrhea Antiretroviral therapy Whipple’s disease
- 6.Chaisson RE, Moore RD, Richman DD, Keruly J, et al. Incidence and natural history of Mycobacterium avium-complex infections in patients with advanced human immunodeficiency virus disease treated with zidovudine, The Zidovudine Epidemiology Study Group. Am Rev Respir Dis. 1992;146:285–289.CrossRefGoogle Scholar
- 19.Shafran SD, Singer J, Zarowny DP, Phillips P, et al. A comparison of two regimens for the treatment of Mycobacterium avium complex bacteremia in AIDS: rifabutin, ethambutol, and clarithromycin versus rifampin, ethambutol, clofazimine, and ciprofloxacin. N Engl J Med. 1996;335:377–383.CrossRefGoogle Scholar