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Digestive Diseases and Sciences

, Volume 63, Issue 11, pp 3120–3125 | Cite as

Prolonged Cecal Insertion Time Is Not Associated with Decreased Adenoma Detection When a Longer Withdrawal Time Is Achieved

  • Cassandra D. L. Fritz
  • Zachary L. Smith
  • Jeffrey Elsner
  • Thomas Hollander
  • Dayna Early
  • Vladimir Kushnir
Original Article

Abstract

Background

The association between withdrawal time and adenoma detection has been established; however, the effect of cecal insertion time on adenoma detection remains unclear.

Aim

To determine the association between cecal insertion time and adenoma detection.

Methods

This study completed a retrospective analysis of data collected in 4 prospective randomized-controlled trials related to screening and surveillance colonoscopy at a single tertiary care from 2010 to 2016. The primary outcome was cecal insertion time and its association with mean number of adenomas per patient and adenoma detection rate (ADR).

Results

1303 patients met inclusion criteria (average age 59.7 ± 8.7 years; 759 females (58.3%), and 763 Caucasians (58.6%). Mean cecal insertion time was significantly longer in patients who were female (p < 0.001), received moderate sedation (p = 0.001), had fellow involvement (p < 0.001), older (p = 0.002), and lower Boston bowel preparation scale (p < 0.001). Withdrawal time was found to increase as mean cecal insertion time increased (p < 0.001). The mean cecal insertion time was not different in patients with or without adenomas (p = 0.94). Cecal insertion time did not correlate with the mean number of adenomas or advanced adenomas per patient (p > 0.05), which was also true on Poisson regression analysis. Adenomas and advanced adenomas per patient were found to decrease when cecal insertion to withdrawal time ratios were greater than 1 (p < 0.001).

Conclusions

Prolonged cecal insertion time was not associated with a decrease in ADR, mean number of adenomas or advanced adenomas per patient. When withdrawal times were longer than cecal insertion times, the number of adenomas and advanced adenomas detected per patient was significantly improved.

Keywords

Cecal insertion time Adenoma detection Withdrawal time Screening colonoscopy Colorectal cancer prevention 

Notes

Author’s contribution

CDLF and VK—conception and design, analysis and interpretation of the data, drafting of the article, critical revision of the article for important intellectual content, final approval of the article. ZLS—conception and design, critical revision of the article for important intellectual content, final approval of the article. JE and TH—conception and design, final approval of the article. DE—conception and design, analysis and interpretation of the data, critical revision of the article for important intellectual content, final approval of the article.

Compliance with ethical standards

Conflict of interest

The authors have no relevant conflicts of interest to disclose.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Cassandra D. L. Fritz
    • 1
  • Zachary L. Smith
    • 2
  • Jeffrey Elsner
    • 2
  • Thomas Hollander
    • 2
  • Dayna Early
    • 2
  • Vladimir Kushnir
    • 2
  1. 1.Barnes Jewish HospitalWashington UniversitySt. LouisUSA
  2. 2.Division of GastroenterologyWashington UniversitySt. LouisUSA

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