Advertisement

Chemistry of Natural Compounds

, Volume 55, Issue 6, pp 1173–1175 | Cite as

Chemical Constituents of Clausena dunniana var. robusta

  • Guojing Wu
  • Yuanfang Sun
  • Shenglan Zhu
  • Yongzhen Xiao
  • Yangguo Xie
  • Ishaq Muhammad
  • Shi-kai YanEmail author
  • Hui-zi JinEmail author
Article
  • 15 Downloads

Clausena dunniana var. robusta is a member of the genus Clausena, which belongs to the Rutaceae family, widely distributed in Hubei, Hunan, and Yunan Provinces. Since antiquity, many species from the genus Clausena have been used for the treatment of asthma, cough, and gastrointestinal diseases. According to previous reports, Clausena species possess a variety of bioactive components, including carbazole alkaloids [1], limonoids [2], and acyclic amides [3]. In order to search for bioactive constituents from this plant, phytochemical investigations were conducted on the leaves and twigs of C. dunniana var. robusta, resulting in the isolation and identification of 10 known compounds, including one furanone, one terpenoid, one lignan, one neolignan, four carbazole alkaloids, one phenylpropanoid, and one limonoid: hydroxydihydrobovolide (1) [4], acortatarinowin H (2) [5], pubinernoid A (3) [6], tatarinoid C (4) [7], clausine Z (5) [8], 2-methoxy-1-(3-methylbuten-1-yl)- 9H-carbazole-3-carba...

References

  1. 1.
    C. Ito, S. Katsuno, M. Itoigawa, N. Ruangrungsi, T. Mukainaka, M. Okuda, Y. Kitagawa, H. Tokuda, H. Nishino, and H. Furukawa, J. Nat. Prod., 63 (1), 125 (2000).CrossRefGoogle Scholar
  2. 2.
    H. M. Xia, C. J. Li, J. Z. Yang, J. Ma, X. G. Chen, D. Zhang, L. Li, and D. M. Zhang, J. Nat. Prod., 77 (4), 784 (2014).CrossRefGoogle Scholar
  3. 3.
    T. S. Wu and Y. R. Liao, Planta Med., 81 (16), 1433 (2015).Google Scholar
  4. 4.
    J. Wu, M. Tsujimori, H. Hirai, and H. Kawagishi, Biosci. Biotechnol. Biochem., 75 (4), 783 (2014).CrossRefGoogle Scholar
  5. 5.
    Y. Lu, Y. Xue, S. Chen, H. Zhu, J. Zhang, X. N. Li, J. Wang, J. Liu, C. Qi, G. Du, and Y. Zhang, Sci. Rep., 6, 22909 (2016).CrossRefGoogle Scholar
  6. 6.
    S. X. Huang, J. Yang, W. L. Xiao, Y. L. Zhu, R. T. Li, L. M. Li, J. X. Pu, X. Li, S. H. Li, and H. D. Sun, Helv. Chim. Acta, 89 (6), 1169 (2010).CrossRefGoogle Scholar
  7. 7.
    X. G. Tong, G. S. Wu, C. G. Huang, Q. Lu, Y. H. Wang, C. L. Long, H. R. Luo, H. J. Zhu, and Y. X. Cheng, J. Nat. Prod., 73 (6), 1160 (2010).CrossRefGoogle Scholar
  8. 8.
    O. Potterat, C. Puder, W. K. Bolek, C. Ke, Y. Ye, and F. Gillardon, Cheminform, 60 (8), 637 (2005).Google Scholar
  9. 9.
    H. Jiang, C. Wang, L. Fan, K. Yang, J. Feng, Z. Geng, J. Xu, Z. Deng, S. Du, and H. Yin, Molecules, 18 (9), 10768 (2013).CrossRefGoogle Scholar
  10. 10.
    W. T. Shung, H. Shiow-Chyn, W. P. Lin, and T. C. Ming, Phytochemistry, 43 (1), 133 (1996).CrossRefGoogle Scholar
  11. 11.
    C. Ito, S. Katsuno, H. Ohta, M. Omura, I. Kajiura, and H. Furukawa, Chem. Pharm. Bull., 45 (12), 48 (1997).CrossRefGoogle Scholar
  12. 12.
    J. Hu and X. Feng, Planta Med., 66 (7), 662 (2000).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Guojing Wu
    • 1
  • Yuanfang Sun
    • 1
  • Shenglan Zhu
    • 1
  • Yongzhen Xiao
    • 1
  • Yangguo Xie
    • 1
  • Ishaq Muhammad
    • 1
  • Shi-kai Yan
    • 1
    Email author
  • Hui-zi Jin
    • 1
    Email author
  1. 1.School of PharmacyShanghai Jiao Tong UniversityShanghaiP. R. China

Personalised recommendations