Chemical Constituents of the Roots of Ormosia hosiei

  • Lin NiEmail author
  • Ya-Tie Qiu
  • Yan Shi
  • Jingxin Chen
  • Hui-You XuEmail author

Ormosia hosiei is one of the species in the genus Ormosia, Leguminosae family, which is widely distributed in south of China [1]. Its roots, twigs, leaves, and seeds were used as traditional Chinese medicine to cure phlogosis, pain, and irregular menstruation [2]. Previous chemical studies have led to the isolation of four alkaloids from O. hosiei [3]. In the course of chemical investigations of the root of the plant, 15 compounds were isolated, all of which were obtained for the first time from this plant, and were identified by ESI-MS and 1H and 13C NMR.

The roots of O. hosiei were collected in Jin An Disrict, Fuzhou, Fujian, People′s Republic of China. The air-dried and powdered roots of O. hosiei (1.6 kg) were extracted two times with 70% EtOH (16 L) at 80°C for 2 h. The EtOH extract (173 g) was passed over a series of chromatographic columns and finally purified by preparative HPLC to yield compounds 1–15.

Lupenone (1) [4], C30H48O, colorless needles (EtOAc), mp 165–167°C. ESI-MS m/z...



This work was supported by the National Natural Science Foundation of China (No. 31700292).


  1. 1.
    H. Sun and M. A. Vincent, Ormosia Jackson, Science Press, China, 2010, 73 pp.Google Scholar
  2. 2.
    Chinese Herbal Medicine, Editorial Committee, Chinese Materia Medica, Shanghai Science and Technology Publishing House, Shanghai, 2005, 579 pp.Google Scholar
  3. 3.
    I. Pouny, M. Batut, L. Vendier, B. David, S. Yi, F. Sautel, P. B. Arimondo, and G. Massiot, Phytochemistry, 107, 97 (2014).CrossRefGoogle Scholar
  4. 4.
    P. Puapairoj, W. Naengchomnong, A. Kijjoa, M. M. Pinto, M. Pedro, M. S. J. Nascimento, A. M. S. Silva, and W. Herz, Planta Med., 71 (3), 208 (2005).CrossRefGoogle Scholar
  5. 5.
    Y. C. Ge, H. J. Zhang, J. X. Lei, and K. W. Wang, Chem. Nat. Compd., 54, 601 (2018).CrossRefGoogle Scholar
  6. 6.
    F. R. Wang, X. Z. Ge, and X. W. Yang, Chin. J. Exp. Trad. Med. Formulae, 17 (20), 61 (2011).Google Scholar
  7. 7.
    J. Sun, Y. D. Yue, F. Tang, X. F. Guo, J. Wang, and X. Yao, Chem. Nat. Compd., 49, 823 (2013).Google Scholar
  8. 8.
    M. X. Zhang, Y. Y. Liu, W. Sun, X. H. Yang, and G. S. Wang, Chem. J. Chin. U., 32 (11), 2554 (2011).Google Scholar
  9. 9.
    X. C. Su, L. Chen, and H. A. Aisa, Chem. Nat. Compd., 44, 365 (2008).CrossRefGoogle Scholar
  10. 10.
    A. Inada, H. Murata, M. Somekawa, and T. Nakanishi, Chem. Pharm. Bull., 40 (11), 3081 (1992).CrossRefGoogle Scholar
  11. 11.
    L. Wu, T. Shen, Y. Z. Zhou, J. Wu, X. Y. Ji, and C. L. Si, Chem. Nat. Compd., 54, 565 (2018).Google Scholar
  12. 12.
    T. Gong, D. X. Wang, P. Liu, and R. Y. Wang, Chin. J. Chin. Mater. Med., 35 (13), 1720 (2010).Google Scholar
  13. 13.
    N. Lami, S. Kadota, T. Kikuchi, and Y. Momose, Chem. Pharm. Bull., 39 (6), 1551 (1991).CrossRefGoogle Scholar
  14. 14.
    M. X. Xiang, H. W. Su, J. Y. Hu, and Y. J. Yan, J. Med. Plant Res., 5 (9), 1685 (2011).Google Scholar
  15. 15.
    M. D. Greca, M. Ferrara, A. Fiorentino, P. Monaco, and L. Previtera, Phytochemistry, 49 (5), 1299 (1998).CrossRefGoogle Scholar
  16. 16.
    A. E. Rodrigues and J. D. P. Araujo, LActualite Chim., 23 (258), 62 (2002).Google Scholar
  17. 17.
    J. Y. Yu, S. J. Zhang, and L. Liu, Chin. Pharm. J., 39 (1), 19 (2005).Google Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.College of Plant ProtectionFujian Agriculture and Forestry UniversityFuzhouP. R. China
  2. 2.Fujian Colleges and University Engineering Research Institute of Conservation & Utilization of Natural BioresourcesFujian Agriculture and Forestry UniversityFuzhouP. R. China

Personalised recommendations