Flavonoids from Verbascum marschallianum and V. orientale

  • M. M. Nykmukanova
  • Zh. B. Mukazhanova
  • K. Kabdysalym
  • B. K. EskalievaEmail author
  • Ahmet Beyatli

The genus Verbascum (Scrophulariaceae) comprises 10 species appearing in Kazakhstan [1] and includes biennial or perennial bushes growing in Central Asia, European Russia, and southern Europe [2].

Iridoids [3], phenylpropanoids, and polyphenolic compounds with various biological activities [4, 5, 6] are the major groups of biologically active compounds from Verbascum plants (mulleins). Extracts of V. marschallianum exhibited high antileishmanial activity [7].

Previously, the flavonoids kaempferol, luteolin, and quercetin [8]; saponins verbascosaponin [9] and ursolic acid [10]; and iridoids aucuboside and catalpol [11] were isolated from EtOAc extracts of several species of this genus.

Aerial parts of V. marschallianum and V. orientalewere collected during budding in 2018 in Eastern-Kazakhstan Oblast. Flavonoids were obtained from milled aerial plant parts (1 kg) by extraction with MeOH for 10 h in a Soxhlet apparatus. The extract was filtered. The pulp was treated with MeOH...


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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • M. M. Nykmukanova
    • 1
  • Zh. B. Mukazhanova
    • 1
  • K. Kabdysalym
    • 1
  • B. K. Eskalieva
    • 2
    Email author
  • Ahmet Beyatli
    • 3
  1. 1.S. Amanzholov East Kazakhstan State University, Department of Natural Sciences and TechnologiesUst-KamenogorskRepublic of Kazakhstan
  2. 2.Al-Farabi Kazakh National University, Department of Chemistry and Chemical TechnologyAlmatyRepublic of Kazakhstan
  3. 3.University of Health Sciences, Department of Medicinal and Aromatic PlantsIstanbulTurkey

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