Two Carotane Sesquiterpenoids from Gymnopus sp. 0612-9 Against Penicillium italicum and P. digitatum, Which Decay Postharvest Citrus
A new carotane sesquiterpenoid, 5-epi-fulvoferruginin (1), and its isomer fulvoferruginin (2), were isolated from the fermentation broth of the wild macrofungus Gymnopus sp. 0612-9. The structures and absolute configurations of compounds 1 and 2 were elucidated by comprehensive spectroscopic analysis and CD exciton chirality method. TLC-bioautography showed that compounds 1 and 2 exhibited moderate activity against pathogens Penicillium italicum and P. digitatum, which are responsible for the decay of postharvest citrus. The 5-epi-fulvoferruginin at C-5 with 5S configuration was weaker than fulvoferruginin at C-5 with 5R configuration.
KeywordsGymnopus sp. 0612-9 5-epi-fulvoferruginin fulvoferruginin activities against Penicillium italicum and P. digitatum
The authors are grateful to Dr. Erwei Li from the Institute of Microbiology, Chinese Academy of Sciences for help in measuring the MS and NMR spectra. This work was supported by the National Natural Science Foundation of China under Grant (No. 31560574), the Key Natural Science Foundation of Jiangxi Province under Grant (No. 20171ACB20014), and the earmarked fund for Jiangxi Agriculture Research System (No. JXARS-20).
- 1.M. S. Ladaniya, Citrus Fruit, Academic Press, San Diego, 2008, 13 pp.Google Scholar
- 3.A. Vitoratos, D. Bilalis, A. Karkanis, and A. Efthimiadou, Notulae Botanicae Horti, Agrobotanici Cluj-Napoca, 41, 86 (2013).Google Scholar
- 4.L. S. Wu, X. Q. Ye, and L. H. Xu, Fujian Agric. (Chinese Journal), 8, 23 (2010).Google Scholar
- 7.S. Wu, G. Huo, Q. Han, and H. Long, Chin. Biotechnol., 36 (2), 51 (2016).Google Scholar
- 8.R. E. Halling, Mycologia Memoir No. 8. Cramer Publ., 148 (1983).Google Scholar
- 9.V. Antonin and M. E. Noordeloos, Libri Botanici, 17, 256 (1997).Google Scholar
- 11.J. L. Mata and C. L. Ovrebo, Fungal Divers., 38, 125 (2009).Google Scholar
- 13.A. Banares, V. Antonin, and G. Moreno, Persoonia – Molecular Phytogeny and Evolution of Fungi, 19 (2), 255 (2007).Google Scholar