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Two New Isoflavones from Phlomis betonicoides and Their Antioxidant Activity

  • Ping Li
  • Wan-Li Zeng
  • Jing Li
  • Tian-dong Zhang
  • Lin Ye
  • Xin Liu
  • Xue-Mei Li
  • Chun-Bo Liu
  • Min Zou
  • Guang-Yu Yang
  • Feng-Mei Zhang
  • Qiu-Fen HuEmail author
Article

Two new isoflavones derivatives, 8,4′-dimethoxy-7-(3-hydroxypropyl)-isoflavone (1) and 8,4′-dimethoxy-7-(3-hydroxypropanoyl)-isoflavone (2), were isolated from the roots of Phlomis betonicoides. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1 and 2 were also tested for the antioxidant activity, and they show good antioxidant activity with an IC50 value of 3.8 and 3.6 μg/mL, respectively.

Keywords

isoflavones Phlomis betonicoides antioxidant activity 

Notes

Acknowledgment

This research was supported by the Research Foundation of China Tobacco Yunnan Industrial Co., Ltd (Nos. 2017JC05 and 2017CP04), the National Natural Science Foundation of China (Nos. 81660717 and 21462051), and the Natural Science Foundation of Yunnan Province (No. 2014FD033).

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Ping Li
    • 1
    • 2
  • Wan-Li Zeng
    • 2
  • Jing Li
    • 2
  • Tian-dong Zhang
    • 2
  • Lin Ye
    • 2
  • Xin Liu
    • 2
  • Xue-Mei Li
    • 2
  • Chun-Bo Liu
    • 2
  • Min Zou
    • 2
  • Guang-Yu Yang
    • 2
  • Feng-Mei Zhang
    • 2
  • Qiu-Fen Hu
    • 1
    Email author
  1. 1.Key Laboratory of Chemistry in Ethnic Medicinal ResourcesYunnan Minzu UniversityKunmingP. R. China
  2. 2.China Tobacco Yunnan Industrial Co., LtdKunmingP. R. China

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