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Chemistry of Natural Compounds

, Volume 55, Issue 4, pp 765–767 | Cite as

Synthesis of Lupeol from Betulin

  • L. R. Garifullina
  • Yu. V. MyasoedovaEmail author
  • N. M. Ishmuratova
Article
  • 22 Downloads

Lupeol (1) is a pentacyclic lupane-type triterpenoid that exhibits important pharmacological properties, e.g., antiangiogenic, antimicrobial, antiproliferative, anti-inflammatory, and cholesterol-lowering. It has demonstrated high pharmacological potential in in vitro and in vivo studies for treating inflammations, arthritis, diabetes, and cardiological and oncological diseases [1, 2]. Therefore, the goal of the work was to develop a modified synthetic scheme for lupeol.

Notes

Acknowledgment

The work used equipment at the Khimiya CUC, UfIC, UFRC, RAS. The work was financially supported by Russian Foundation for Basic Research Grant 17-03-01050 A.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • L. R. Garifullina
    • 1
  • Yu. V. Myasoedova
    • 1
    Email author
  • N. M. Ishmuratova
    • 1
  1. 1.Ufa Institute of Chemistry, Subdivision of Ufa Federal Research CentreRussian Academy of SciencesUfaRussia

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