Phenol Glycosides from Root Bark of Phellodendron chinense
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Phellodendron chinense is a plant of Rutaceae, mainly distributed at 800–1500 meters above sea level. In China, the plants are distributed in Sichuan, Hubei, Guizhou, Yunnan, Shaanxi, Guangxi, and other places . P. chinense is very well known for its diversified chemistry, particularly by the presence of alkaloids, limonin, phenolic acids, terpenoids, lignans, sterols, and their glycosides . Most of the previous phytochemical investigations have focused on petroleum ether, ethyl acetate, and n-butanol fractions of P. chinense extract, while the water fraction of its extract was rarely reported.
Root bark of Phellodendron chinense were collected from Shanghai of China in 2015. Dried root bark of P. chinense (20 kg) were extracted with 60% acetone (10 L × 3) at room temperature. The combined acetone solvent was filtered and concentrated under reduced pressure to give 962 g of residue. The residue was then suspended in water and partitioned successively with petroleum ether and n-bu...
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