Phenolic Compounds from Vernonia anthelmintica Seeds
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Metabolites of natural products have recently drawn attention because of their therapeutic potential and are used to treat various diseases.
The plant Vernonia anthelmintica (Asteraceae) is broadly distributed in high-mountain sites of South Xinjiang, India, and Pakistan. Seeds of V. anthelmintica are known as Kali Zeeri and are used in Chinese folk medicine. The traditional Uyghur medicine tractate reports its therapeutic use to treat vitiligo. Previous phytochemical studies found various constituents including elemanolide dimers, sesquiterpenoids, flavonoids, steroids, and caffeoylquinic acids [1, 2].
Herein, results from phytochemical studies of the MeOH fraction of V. anthelmintica are communicated. The biologically active compounds included nine phenolic compounds (1–9), the antioxidant activity of which was verified by DPPH analysis. The structures of the compounds were established using spectral data (1D and 2D NMR and ESI-MS) and literature data. A literature search showed...
The work was sponsored by the West Light Foundation of the Chinese Academy of Sciences (No. 2016-QNXZ-B-1) and the Central Asian Center of Drug Discovery and Development, Chinese Academy of Sciences.
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