Chemistry of Natural Compounds

, Volume 55, Issue 4, pp 671–673 | Cite as

A New Eremophilane Sesquiterpene with Nematocidal Activity from Ligularia veitchiana

  • Hai-bo WuEmail author
  • Ting-ting Liu
  • Wen-jie Deng
  • Jing Zhang
  • Luo-wenlei Yang

A new eremophilane sesquiterpene, 10α-hydroxy-3-oxoeremophil-1(2),7(11),8(9)-trien-8(12)-olide (1), was isolated from Ligularia veitchiana. The structure of the new compound was elucidated by physical and spectroscopic data analysis, including 1D NMR and 2D NMR and HR-ESI-MS. Compound 1 showed inhibitory activity against the second-stage juveniles (J2) of Meloidogyne incognita with an LC50 value of 134.5 mg/L.


Ligularia veitchiana eremophilane sesquiterpene Meloidogyne incognita nematocidal activity 



This work was supported by the National Science Foundation of China (Grant No. 31570407) and the National College Students Innovation and Entrepreneurship Training Program (Grant No. GCCX2018110011).


  1. 1.
    H. B. Lu, S. Y. Xu, W. J. Zhang, C. M. Xu, B. X. Li, D. X. Zhang, W. Mu, and F. Liu, J. Agric. Food Chem., 65, 544 (2017).CrossRefGoogle Scholar
  2. 2.
    Y. J. Liu, Y. Liu, and K. Q. Zhang, Chem. Nat. Compd., 44, 203 (2008).CrossRefGoogle Scholar
  3. 3.
    Q. Liu, L. Shen, T. T. Wang, C. J. Chen, W. Y. Qi, and K. Gao, Food Chem., 122, 55 (2010).CrossRefGoogle Scholar
  4. 4.
    Y. Zhao, Z. J. Jia, R. X. Tan, and L. Yang, Phytochemistry, 31, 2785 (1992).CrossRefGoogle Scholar
  5. 5.
    Y. Zhao, S. Parsons, B. A. Smart, R. Tan, Z. J. Jia, H. Sun, and D. W. Rankin, Tetrahedron, 53, 6195 (1997).CrossRefGoogle Scholar
  6. 6.
    Z. J. Jia, Y. Zhao, and R. Tan, J. Nat. Prod., 56, 494 (1993).CrossRefGoogle Scholar
  7. 7.
    J. L. Yang, R. Wang, and Y. P. Shi, Nat. Prod. Bioprospect., 1, 1 (2011).CrossRefGoogle Scholar
  8. 8.
    W. S. Wang, K. Gao, and Z. J. Jia, J. Chin. Chem. Soc., 51, 417 (2004).CrossRefGoogle Scholar
  9. 9.
    J. J. Chen, C. J. Chen, X. J. Yao, X. J. Jin, and K. Gao, J. Nat. Prod., 77, 1329 (2014).CrossRefGoogle Scholar
  10. 10.
    Z. Samek, J. Harmatha, L. Novotny, and F. Sorm, Coll. Czech. Chem. Commun., 34, 2792 (1969).CrossRefGoogle Scholar
  11. 11.
    Y. Bi, C. Gao, and Z. Yu, J. Agric. Food Chem., 66, 3833 (2018).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Hai-bo Wu
    • 1
    • 2
    Email author
  • Ting-ting Liu
    • 1
  • Wen-jie Deng
    • 1
  • Jing Zhang
    • 1
  • Luo-wenlei Yang
    • 1
  1. 1.College of Life and Environmental ScienceMinzu University of ChinaBeijingP. R. China
  2. 2.Beijing Engineering Research Center of Food Environment and healthMinzu University of ChinaBeijingP. R. China

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