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Two New Pairs of Epimeric Pyrrolizidine Alkaloids from Liparis nervosa

  • Lin Chen
  • Jing Li
  • Shuai Huang
  • Xianli ZhouEmail author
Article

Two new pairs of epimeric pyrrolizidine alkaloids, nervosine XVI/XVII and XVIII/XIX were isolated from the whole plant of Liparis nervosa. Their structures were elucidated by extensive spectroscopic analyses including 1D, 2D NMR, and HR-ESI-MS.

Keywords

Liparis nervosa pyrrolizidine alkaloid epimeric 

Notes

Acknowledgment

This work was supported by the National Natural Science Foundation of China under grants (81402803 and 21807089), the Research Foundation for Educational Commission of Sichuan Province (15TD0048), the Opening Project of Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province (CSPC 201801).

References

  1. 1.
    Y. X. Hua, S. F. Liu, and Z. Q. Yang, The Chinese Herbal, Science and Technology Publishing House, Shanghai, 1999, 997 pp.Google Scholar
  2. 2.
    S. Huang, X. L. Zhou, C. J. Wang, H. Y. Wang, Y. S. Wang, L. H. Shan, and J. Weng, Planta Med., 79, 281 (2013).CrossRefGoogle Scholar
  3. 3.
    S. Huang, M. F. Pan, X. L. Zhou, Z. L. Zhou, C. J. Wang, L. H. Shan, and J. Weng, Chin. Chem. Lett., 24, 734 (2013).CrossRefGoogle Scholar
  4. 4.
    S. Huang, X. L. Zhou, C. J. Wang, Y. S. Wang, F. Xiao, L. H. Shan, Z. Y. Guo, and J. Weng, Phytochemistry, 93, 154 (2013).CrossRefGoogle Scholar
  5. 5.
    S. Huang, D. X. Zhong, L. H. Shan, Y. Z. Zheng, Z. K. Zhang, Y. H. Bu, H. W. Ma, and X. L. Zhou, Chin. Chem. Lett., 27, 757 (2016).CrossRefGoogle Scholar
  6. 6.
    L. Chen, S. Huang, C. Y. Li, F. Gao, and X. L. Zhou, Phytochemistry, 153, 147 (2018).CrossRefGoogle Scholar
  7. 7.
    K. Nishikawa and Y. Hirata, Tetrahedron Lett., 27, 2591 (1967).CrossRefGoogle Scholar
  8. 8.
    K. Nishikawa and Y. Hirata, Tetrahedron Lett., 60, 6289 (1968).CrossRefGoogle Scholar
  9. 9.
    R. Hanada, F. Abe, Y. Mori, and T. Yamauchi, Chem. Pharm. Bull., 40, 2913 (1992).CrossRefGoogle Scholar
  10. 10.
    J. A. Duan, L. Wang, S. Qian, S. Su, and Y. Tang, Arch. Pharm. Res., 31, 965 (2008).CrossRefGoogle Scholar
  11. 11.
    U. Friedrich, K. Siems, P. N. Solis, M. P. Gupta, and K. Jenett-Siems, Pharmazie, 60, 455 (2005).Google Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, School of Chemistry and Chemical EngineeringChina West Normal UniversityNanchongP. R. China
  2. 2.School of Life Science and EngineeringSouthwest Jiaotong UniversityChengduP. R. China

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