Advertisement

Neuroprotective Sesquiterpenes from Capsella bursa-pastoris

  • Qinge Ma
  • Rongrui Wei
  • Zhongling Cao
Article

Capsella bursa-pastoris belongs to the Brassicaceae family and is consuned as a popular vegetable in folk recipes. C. bursa-pastoris is an annual or biennial herb that is widely distributed in most areas of China. Moreover, C. bursa-pastoris has always been used as a medicinal plant for treating metrorrhagia, conjunctivitis, vomiting, and hydropsy [1]. Previous phytochemical investigations of C. bursa-pastoris have displayed the presence of flavonoids [2], essential oils [3], amino acids [4], and alkaloids [5]. Modern pharmacology has revealed that C. bursa-pastoris has many biological activities, such as hepatoprotective [6], anti-oxidant [7], anti-tumor [8], anti-microbial [9], anti-hypertensive [10], and anti-inflammatory [11].

To the best of our knowledge, there have been no reports on the neuroprotective activities of C. bursa-pastoris, which prompted us to investigate further its pharmacological potentials. As a result, 12 compounds (112) were isolated and identified as...

Notes

Acknowledgment

This work was supported by the Key Scientific Research Project of Colleges and Universities in Henan Province (Based PC12 Cell-Studies on Neuroprotective Components of Magnolia biondii Pamp.).

References

  1. 1.
    Q. H. Wang, Y. T. Na, and E. Q. Wu, Nat. Prod. Res. Dev., 26, 50 (2014).Google Scholar
  2. 2.
    N. Song, R. R. Wang, Z. L. Li, X. Q. Liu, W. Li, and Y. H. Pei, Chin. J. Magn. Reson., 26, 88 (2009).Google Scholar
  3. 3.
    Y. X. Gao and X. J. Zhou, Res. Dev. Market, 25, 1070 (2009).Google Scholar
  4. 4.
    F. M. Xu, T. Morikawa, H. Matsuda, K. Ninomiya, and M. Yoshikawa, J. Nat. Prod., 67, 569 (2004).CrossRefGoogle Scholar
  5. 5.
    M. Pan, Chem. Bioeng., 23, 33 (2006).Google Scholar
  6. 6.
    Q. G. Ma, Y. M. Guo, R. R. Wei, Z. P. Sang, W. M. Liu, L. Gao, and T. T. Liu, Rev. Bras. Farmacogn., 26, 710 (2016).CrossRefGoogle Scholar
  7. 7.
    H. Zhang, G. H. Li, Y. J. Yang, and C. X. Nan, Jiangsu Agric. Sci., 4, 225 (2008).Google Scholar
  8. 8.
    K. Kelko, A. Mitsutaro, K. Masayoshi, and M. Komel, Cancer Res., 36, 1900 (1976).Google Scholar
  9. 9.
    Y. J. Yang, C. Y. Liang, and F. S. Cui, Sci. Tech. Food Ind., 31, 146 (2010).Google Scholar
  10. 10.
    X. M. Huang, J. Cai, and H. Y. Zhang, J. Liaoning Coll. TCM., 7, 425 (2005).Google Scholar
  11. 11.
    X. R. Yue, Y. Yuan, Y. Zhao, and S. S. Wang, Lishizhen Med. Mater. Med. Res., 18, 871 (2007).Google Scholar
  12. 12.
    Q. G. Ma, K. Xu, Z. P. Sang, R. R. Wei, W. M. Liu, Y. L. Su, J. B. Yang, A. G. Wang, T. F. Ji, and L. J. Li, Bioorg. Med. Chem. Lett., 26, 799 (2016).CrossRefGoogle Scholar
  13. 13.
    Q. G. Ma, T. Li, R. R. Wei, W. M. Liu, Z. P. Sang, and Z. W. Song, J. Agr. Food Chem., 64, 8138 (2016).CrossRefGoogle Scholar
  14. 14.
    J. Kwon, N. T. Hiep, D. W. Kim, B. Y. Hwang, H. J. Lee, M. W. Mar, and D. Lee, J. Nat. Prod., 77, 1893 (2014).CrossRefGoogle Scholar
  15. 15.
    J. M. Qiu, X. Wang, and C. G. Song, Fitoterapia, 109, 75 (2016).CrossRefGoogle Scholar
  16. 16.
    J. H. Ma, Y. Wang, Y. Liu, S. Y. Gao, L. Q. Ding, F. Zhao, L. X. Chen, and F. Qiu, Fitoterapia, 103, 90 (2015).CrossRefGoogle Scholar
  17. 17.
    P. Somwong, R. Suttisri, and A. Buakeaw, Fitoterapia, 85, 1 (2013).CrossRefGoogle Scholar
  18. 18.
    B. Jiang, W. J. Wang, M. P. Li, X. J. Huang, F. Huang, H. Gao, P. H. Sun, M. F. He, Z. J. Jiang, X. Q. Zhang, and W. C. Ye, Bioorg. Med. Chem. Lett., 23, 3879 (2013).CrossRefGoogle Scholar
  19. 19.
    Y. Shiono, H. Koyama, T. Murayama, and T. Koseki, Phytochem. Lett., 14, 143 (2015).CrossRefGoogle Scholar
  20. 20.
    G. Y. Xia, L. Zhou, J. H. Ma, Y. Wang, L. Q. Ding, F. Zhao, L. X. Chen, and F. Qiu, Fitoterapia, 103, 143 (2015).CrossRefGoogle Scholar
  21. 21.
    S. Li, H. Huang, J. Liu, T. Song, K. Wu, Y. F. Han, and M. Xia, Phytochem. Lett., 6, 315 (2013).CrossRefGoogle Scholar
  22. 22.
    H. Zhu, X. X. Hua, T. Gong, J. Pang, Q. Hou, and P. Zhu, Phytochem. Lett., 6, 392 (2013).CrossRefGoogle Scholar
  23. 23.
    R. W. Doskotch, C. D. Hufford, and F. S. El-Feraly, J. Org. Chem., 37, 2740 (1972).CrossRefGoogle Scholar
  24. 24.
    F. Bohlmann, J. Jakupovic, N. Ates, A. Schuster, J. Pickardt, R. M King, and H. Robinson, Liebigs Ann. Chem., 6, 962 (1983).CrossRefGoogle Scholar
  25. 25.
    F. Bohlmann, P. K. Mahanta, J. Jakupovic, R. C. Rastogi, and A. A. Natu, Phytochemistry, 17, 1165 (1978).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.State Key Laboratory of Innovative Drugs and High Efficiency Energy Saving and Consumption Reduction Pharmaceutical Equipment, Key Laboratory of Modern Preparation of TCM of Ministry of Education, Research Center of Natural Resources of Chinese Medicinal Materials and Ethnic MedicineJiangxi University of Traditional Chinese MedicineNanchangP. R. China
  2. 2.College of Chemistry and Pharmaceutical EngineeringNanyang Normal UniversityNanyangP. R. China

Personalised recommendations