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New Heterocyclic Pyrano[2′,3′:5,6]Chromeno[3,2-c]Pyridin-4-Ones and Furo[2′,3′:5,6]Chromeno[3,2-c]Pyridin-3(2H)-Ones Synthesized Via a Hetero-Diels–Alder Reaction

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Chemistry of Natural Compounds Aims and scope

The behavior of flavonoid Mannich bases in inverse electron-demand hetero-Diels–Alder reactions was studied. Isoflavones and aurones were used as examples to show that their Mannich bases reacted with 4-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)morpholine through an elimination mechanism and subsequent cycloaddition to form derivatives of the new heterocyclic systems pyrano[2′,3′:5,6]chromeno[3,2-c]pyridin-4-one and furo[2′,3′:5,6]chromeno[3,2-c]pyridin-3(2H)-one.

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Authors and Affiliations

  1. Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, 1 Murmanskaya St., Kiev, 02094, Ukraine

    A. V. Popova, G. P. Mrug, K. M. Kondratyuk & M. S. Frasinyuk

  2. National University of Food Technologies, 68 Vladimirskaya St., Kiev, 01601, Ukraine

    S. P. Bondarenko

Authors
  1. A. V. Popova
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  2. G. P. Mrug
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  3. K. M. Kondratyuk
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  4. S. P. Bondarenko
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  5. M. S. Frasinyuk
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Corresponding author

Correspondence to M. S. Frasinyuk.

Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2016, pp. 859–862.

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Popova, A.V., Mrug, G.P., Kondratyuk, K.M. et al. New Heterocyclic Pyrano[2′,3′:5,6]Chromeno[3,2-c]Pyridin-4-Ones and Furo[2′,3′:5,6]Chromeno[3,2-c]Pyridin-3(2H)-Ones Synthesized Via a Hetero-Diels–Alder Reaction. Chem Nat Compd 52, 1000–1004 (2016). https://doi.org/10.1007/s10600-016-1846-6

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  • DOI: https://doi.org/10.1007/s10600-016-1846-6

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