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Synthesis of quinazolin-4(3H)-ones via the reaction of isatoic anhydride with benzyl azides in the presence of potassium tert-butoxide in DMSO

  • Mohammad Hosein SayahiEmail author
  • Saeed Bahadorikhalili
  • Mohammad Mahdavi
  • Laleh Baghshirin
Article
  • 4 Downloads

In this paper, a novel method is described for the synthesis of quinazolin-4(3H)-one derivatives via the reaction of isatoic anhydride with benzyl azides in the presence of potassium tert-butoxide in DMSO. The reaction is completed after 4 h at 100°C to produce the title products in good yields.

Keywords

benzyl azides isatoic anhydride potassium tert-butoxide quinazolin-4(3H)-ones 

Notes

This research was supported by grants from the Payame Noor University.

Supplementary material

10593_2019_2563_MOESM1_ESM.pdf (1 mb)
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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Mohammad Hosein Sayahi
    • 1
    Email author
  • Saeed Bahadorikhalili
    • 2
  • Mohammad Mahdavi
    • 3
  • Laleh Baghshirin
    • 1
  1. 1.Department of ChemistryPayame Noor UniversityTehranIran
  2. 2.School of Chemistry, College of ScienceUniversity of TehranTehranIran
  3. 3.Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences InstituteTehran University of Medical SciencesTehranIran

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