Chemistry of Heterocyclic Compounds

, Volume 55, Issue 10, pp 933–935 | Cite as

Open image in new window Hetaryl-substituted bicyclo[1.1.1]pentanes (microreview)

  • Oleksandr O. GrygorenkoEmail author
  • Serhii O. Kokhan

Open image in new window Synthesis and properties of heterocycles bearing bicyclo[1.1.1]pentane moiety attached to the heterocyclic ring are summarized in this microreview. In particular, heterocyclizations with bicyclo-[1.1.1]pentane derivatives, as well as reactions involving incorporation of the preexisting heterocyclic system into the bicyclo[1.1.1]pentane core are discussed.


The funding of this work by Enamine Ltd. is acknowledged. Oleksandr O. Grygorenko was also funded by the Ministry of Education and Science of Ukraine (grant No. 19BF037-03). The authors thank Prof. Andrey A. Tolmachev for his encouragement and support.


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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Enamine Ltd.KyivUkraine
  2. 2.Taras Shevchenko National University of KyivKyivUkraine

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