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Chemistry of Heterocyclic Compounds

, Volume 55, Issue 8, pp 725–728 | Cite as

Catalyst-free three-component synthesis of 2-amino-4,6-diarylpyridine-3-carbonitriles under solvent-free conditions

  • Mohammad Hosein SayahiEmail author
  • Seyyed Jafar Saghanezhad
  • Mohammad Mahdavi
Article
  • 18 Downloads

A novel efficient one-pot synthesis of 2-amino-4,6-diarylpyridine-3-carbonitriles is described. Method involves heating the mixture of an acetophenone oxime, aldehyde, and malononitrile without any catalyst under solvent-free conditions to give the title compounds in good to high yields.

Keywords

acetophenone oximes 2-amino-4,6-diarylpyridine-3-carbonitriles solvent-free synthesis 

Supplementary material

10593_2019_2527_MOESM1_ESM.pdf (401 kb)
ESM 1 (PDF 401 kb)

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Mohammad Hosein Sayahi
    • 1
    Email author
  • Seyyed Jafar Saghanezhad
    • 2
  • Mohammad Mahdavi
    • 3
  1. 1.Department of ChemistryPayame Noor UniversityTehranIran
  2. 2.ACECR-Production Technology Research InstituteAhvazIran
  3. 3.Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences InstituteTehran University of Medical SciencesTehranIran

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