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Chemistry of Heterocyclic Compounds

, Volume 55, Issue 4–5, pp 463–464 | Cite as

Peculiarities of cyclization of 2-(2-oxo-2-phenylethylidene)-2,3-dihydropyrimidin-4(1Н)-one with ethyl cyanoacetate

  • Arkadii А. Yavolovskii
  • Lidiya V. Grishchuk
  • Sergei M. Pluzhnik-GladyrEmail author
  • Yurii E. Ivanov
  • Ildar M. Rakipov
  • Dmitrii E. Stepanov
  • Gerbert L. Kamalov
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The reaction of 2-(2-oxo-2-phenylethylidene)-2,3-dihydropyrimidin-4(1H)-ones and ethyl cyanoacetate leads to the formation of 4-hydroxy-2,10-dioxo-5-phenyl-1,10-dihydro-2H-pyrimido[1,2-a][1,8]naphthyridine-3-carbonitriles.

Keywords

3-cyanopyridin-2(1Н)-ones ethyl cyanoacetate pyrimidine pyrimido[1,2-a][1,8]naphthyridine 

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Arkadii А. Yavolovskii
    • 1
  • Lidiya V. Grishchuk
    • 1
  • Sergei M. Pluzhnik-Gladyr
    • 1
    Email author
  • Yurii E. Ivanov
    • 1
  • Ildar M. Rakipov
    • 1
  • Dmitrii E. Stepanov
    • 1
  • Gerbert L. Kamalov
    • 1
  1. 1.A. V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of UkraineOdessaUkraine

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