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Chemistry of Heterocyclic Compounds

, Volume 55, Issue 4–5, pp 307–311 | Cite as

Synthesis and transformation features of 2-(2-oxo-2-arylethylidene)-2,3-dihydropyrimidin-4(1Н)-ones

  • Arkadii A. Yavolovskii
  • Lidiya V. Grishchuk
  • Yurii E. Ivanov
  • Sergei M. Pluzhnik-GladyrEmail author
  • Gerbert L. Kamalov
Article
  • 13 Downloads

This article describes the synthesis of 2-(2-oxo-2-arylethylidene)-2,3-dihydropyrimidin-4(1Н)-ones and provides details of their reactivity, such as nucleophilic and electrophilic substitution, as well as associated processes: acidic degradation, isomerization, and diazine ring cleavage.

Keywords

pyrimidines acidic degradation mechanochemical activation nucleophilic and electrophilic substitution sulfide contraction 

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Arkadii A. Yavolovskii
    • 1
  • Lidiya V. Grishchuk
    • 1
  • Yurii E. Ivanov
    • 1
  • Sergei M. Pluzhnik-Gladyr
    • 1
    Email author
  • Gerbert L. Kamalov
    • 1
  1. 1.A. V. Bogatsky Physico-Chemical InstituteNational Academy of Sciences of UkraineOdessaUkraine

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