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Chemistry of Heterocyclic Compounds

, Volume 54, Issue 9, pp 868–874 | Cite as

Synthesis and antimycobacterial activity of pyridinium compounds with sulfonylacetamide substituent in N-alkyl chain

  • Marina M. Shulaeva
  • Marionella A. Kravchenko
  • Vyacheslav E. Semenov
Article
  • 31 Downloads

Pyridines containing amine, amide, or hydrazide substituent were quaternized with (ω-haloalkyl)sulfonylacetamides, resulting in new pyridinium compounds that exhibited tuberculostatic activity against the strain H37Rv of Mycobacterium tuberculosis.

Keywords

carbamoylmethylsulfonyl group pyridinium compounds sulfonylacetamides quaternization antituberculosis activity 

Notes

This study received financial support from the Russian Science Foundation (project 14-50-00014).

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Marina M. Shulaeva
    • 1
  • Marionella A. Kravchenko
    • 2
  • Vyacheslav E. Semenov
    • 1
  1. 1.A. E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific CenterRussian Academy of SciencesKazanRussia
  2. 2.Ural Research Institute of Phthysiopulmonology – branch of the National Medical Research Center of Phthysiopulmonology and Infectious DiseasesMinistry of Health of the Russian FederationYekaterinburgRussia

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