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Chemistry of Heterocyclic Compounds

, Volume 54, Issue 8, pp 765–772 | Cite as

Observations from aminomethylation of 7-substituted 6-hydroxyaurones

  • Svitlana P. Bondarenko
  • Mykhaylo S. Frasinyuk
Article
  • 33 Downloads

Aminomethylation of 7-substituted 6-hydroxyaurones was studied using primary and secondary amines. In the case of 6-hydroxy-7-methylaurones, their 5-dialkylaminomethyl derivatives or 7-benzylidene-3,4-dihydro-2Н-furo[3,2-g][1,3]benzoxazin-6(7Н)-ones were formed. The aminomethylation reaction of 6,7-dihydroxyaurones produced only 5-aminomethyl derivatives.

Keywords

aurone furo[3,2-g][1,3]benzoxazin-6(7Н)-one Mannich base aminomethylation 

Supplementary material

10593_2018_2347_MOESM1_ESM.pdf (3.8 mb)
ESM 1 (PDF 3908 kb)

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Svitlana P. Bondarenko
    • 1
  • Mykhaylo S. Frasinyuk
    • 2
  1. 1.National University of Food TechnologiesKyivUkraine
  2. 2.Institute of Bioorganic Chemistry and PetrochemistryNational Academy of Sciences of UkraineKyivUkraine

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