Biomedical Microdevices

, 21:83 | Cite as

Ultra-low-cost fabrication of polymer-based microfluidic devices with diode laser ablation

  • Kexin Gao
  • Jingji Liu
  • Yiqiang FanEmail author
  • Yajun Zhang


In this work, a diode laser ablation approach was used for the fabrication of PMMA-based microfluidic devices. Compared with the conventional CO2 or femtosecond laser fabrication method, the proposed laser ablation method based on diode laser significantly lowered the cost in the fabrication of polymer-based microfluidic devices with comparable resolution and surface quality. PMMA substrate was used for the laser ablation process, due to the transparency of PMMA in the diode laser’s working wavelength, a layer of Kraft tape was applied on the surface of PMMA for the absorption of laser energy, and microchannels were then achieved on the surface of PMMA with the proposed low-cost diode laser system. The comparison between the proposed method and the CO2 laser ablation method was also conducted in this study. The profile of the fabricated microchannels was carefully characterized, several microfluidic devices were also fabricated for the demonstration of the proposed fabrication method using a diode laser.


Microfluidics Low-cost PMMA Diode laser 



This work was supported by the National Natural Science Foundation of China (No. 51804014) and Beijing Natural Science Foundation (2182055).


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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.School of Mechanical and Electrical EngineeringBeijing University of Chemical TechnologyBeijingChina
  2. 2.School of Engineering and Applied SciencesHarvard UniversityCambridgeUSA

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